Antimicrobial resistance is a serious global threat, causing treatment of even minor infections to become challenging and expensive1. When bacteria are starved or stressed, they can become resistant to antibiotics through activation of certain stress response pathways. This leads to decreased bacterial metabolism, biofilm formation, increased production of virulence factors, and ultimately a bacterial growth state that is more resilient…
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Recently, Dr. Ross MacGillivray, Professor of Biochemistry and Molecular Biology and one of the founding members of the CBR, retired after almost 37 years of work and dedication. Dr. MacGillivray served as the first Director of the CBR. His research focused on human blood proteins involved in coagulation and iron homeostasis. We interviewed him about his experience during all these…
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A $24-million donation to the University of British Columbia’s faculty of medicine will expand research aimed at helping people live longer and enjoy a better quality of life in their later years. The donation, from businessman, philanthropist and UBC alumnus Edwin S.H. Leong, is the largest gift that UBC’s medical school has ever received from an individual. “My wish is…
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New research by the Faculty of Medicine suggests that a strict eating schedule can help clear away the protein responsible for Huntington disease in mice. Huntington disease (HD) is an inherited, progressive disorder that causes involuntary movements and psychiatric problems. Symptoms appear in adulthood and worsen over time. Children born to a parent with HD have a one in two…
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AbCellera Biologics Inc. announced today that it was awarded a contract from the Defense Advanced Research Projects Agency (DARPA) to develop rapid countermeasures against viral outbreaks. Over the four-year contract, AbCellera will receive up to USD $30 million in funding to establish an end-to-end platform for rapid pandemic response, and will lead an internationally recognized team of experts in virology,…
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Health care experts are quick to remind us that a healthy lifestyle includes regular exercise. But what if certain, potentially life-saving medications don’t perform as well during exercise? Peter Ruben and his team of researchers have spent years studying why seemingly healthy patients with inherited cardiac arrhythmias can sometimes suddenly die during exercise. (2017, 2016, 2015) His past research has shown that…
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Bringing Multiple Sclerosis out of the Dark

New study shines light on lifetime sun exposure and multiple sclerosis. Rates of multiple sclerosis (MS) are typically higher in northern countries, where sunlight is in shorter supply. These rates have led researchers to consider increased sunlight exposure—particularly in the form of ultraviolet or UV-B rays—as a possible prevention for this autoimmune disease. But the specifics of this relationship remain…
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Two members of the Faculty of Medicine are leading a five-year project that aims to improve personalized treatments for patients with pancreatic cancer. The Enhanced Pancreatic Cancer Profiling for Individualized Care (EPPIC) aims to sequence metastatic pancreatic tumours of 400 patients in Quebec, Ontario, Alberta and British Columbia.  They hope to improve understanding of pancreatic cancer biology to individualize treatment strategies,…
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STEMCELL Technologies has signed an exclusive license with Indiana University Innovation and Commercialization Office for patented rights to groundbreaking inner ear organoid technologies. The inner ear contains organs responsible for detecting sounds and maintaining balance, both of which are mediated by a sensory cell called the hair cell due to its specialized protrusions resembling tiny hairs. Hair cell dysfunction can…
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e million Canadians suffer from a rare disease. In Dr. Bill Gibson’s lab at BC Children’s Hospital, scientists are studying rare mutations and their effects on the human body. Their efforts are helping doctors care for children with rare diseases and revealing the origins of more common health conditions. In a study recently published in Diabetes by Dr. Gibson and PhD student Chi…
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