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SUMMARY:Plasmonic Nanoparticles for Use in Nanomedicine
DESCRIPTION:Plasmonic nanoparticles such as gold\, silver\, or their alloys are interesting nanomaterials for application in nanomedicine therapeutics and diagnostics. In this talk\, I will briefly introducing plasmonic nanoparticle characteristics\, then discuss recent developments in this field at Polytechnique. \nAmong the developments I will describe is a new method for delivering exogenous biomolecules into targeted cells using an ultrafast laser and plasmonic nanoparticles. We have used the technique of plasmon-mediated laser nanosurgery to effectively perform gene transfection in various living cells and delivery of biomolecules in vivo in animal models for ophthalmic applications. I will share some of our recent results on laser trigger release of antitumor drugs from lipid nanoparticles containing gold nanoparticles. \nMoreover\, we have synthesized alloy nanoparticles using an improved seeded-growth approach. We use these spectrally distinctive plasmonic nanoparticles  as biomarkers to perform quantitative multiplexed 3D imaging of cells and tissues. This technology has been commercialized by our spin-off company\, Vega BioImaging\, to assist pathologists with their diagnostics. \nOur plasmonic-based techniques show promise as innovative tools for basic research in biology and medicine\, and could be adapted for use as therapeutic\, diagnostic\, and theranostic clinical tools.
URL:https://scienceinvancouver.com/event/plasmonic-nanoparticles-for-use-in-nanomedicine/
LOCATION:Online
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