Zymeworks Inc. (“Zymeworks”), a clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation multifunctional biotherapeutics, initially focused on the treatment of cancer, today announced that it has filed a registration statement on Form F-1 (the “Registration Statement”) with the U.S. Securities and Exchange Commission (the “SEC”) and a preliminary prospectus with the securities regulatory authorities in each…
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Two Stories of Transition Success

Success is such an arbitrary measure. “My main advice is to create your own definition of success”, recommends Grace Lee, a transition expert. “Very often we let everyone else define what it means to be successful: a great career, a family… In our field, articles became the currency of success, but that is not what defines you”. Grace metamorphosed a…
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The panel charged with reviewing the federal government’s support of fundamental science released its final report on April 10, laying out a multi-year strategy that includes greater investment in independent investigator-led projects, better coordination between the four core research funding agencies and the creation of an oversight body called the National Advisory Council on Research and Innovation. The panel also…
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My PhD journey is coming to its end and I am considering a non-academic career. Looking at job descriptions, I know I tick the box marked ‘strong analytical and problem-solving skills.’ However, there are other boxes to consider: ‘Strong time and project management skills.’ ‘A team player with a proven track record of collaborations.’ ‘The ability to communicate clearly and…
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Dr. Catalina Lopez-Correa is the Chief Scientific Officer (CSO) of Genome BC and former CSO of Genome Quebec. Formally trained as both a medical physician and scientific researcher, her background in biotech, pharmacy, and corporate America allowed her to travel the world while preparing her for her current position. We sat down with Dr. Lopez-Correa to discuss her journey from…
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Cellular Dynamics International (CDI), a FUJIFILM company and a leading developer and manufacturer of induced pluripotent stem cell-derived products, today announced it has signed a distribution agreement with STEMCELL Technologies, a world leader in iPS cell culture media. “This joint agreement with STEMCELL Technologies will make iPSC technology widely available to researchers worldwide, helping advance biological research leading to cellular…
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Researchers Find More Multiple Sclerosis-Causing Mutations

Less than a year after publishing research identifying a single genetic mutation that caused multiple sclerosis (MS) in two Canadian families, scientists at the University of British Columbia have found a combination of two other mutations in another family that made them highly susceptible to the disease. The “double gene” mutation was identified in a large Canadian family with five…
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Imagine this: What if scientists had a tool that allowed them to edit genes directly, altering their underlying DNA? The science-fictional applications, like designer babies or Frankensteined organisms, would be obvious—although ethical and legal rules in science and medicine might prevent such uses. Immediate applications would be more mundane, but also more significant: understanding and treating disease, manufacturing new types…
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Tyrosine kinase inhibitor (TKI) therapies induce clinical remission with remarkable effects on chronic myeloid leukemia (CML). However, very few TKIs completely eradicate the leukemic clone and persistence of leukemic stem cells (LSCs) remains challenging, warranting new, distinct targets for improved treatments. We demonstrated that the scaffold protein AHI-1 is highly deregulated in LSCs and interacts with multiple proteins, including Dynamin-2…
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A Growing Phobia

Supervisor phobia, as I call it, is an irrational fear that I have seen often among trainees in my 30-plus years as a faculty member. Yes, some principal investigators are harsh and unsupportive. But in my experience, this phobia is unrelated to a supervisor’s behaviour — or even to a graduate student’s or postdoc’s initial promise. Instead, it describes junior…
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