His research is currently focused on developing clinically translatable technology platforms to combat cancer. His lab discovered porphysome nanotechnology (Nature Materials 2011), named one of the “top 10 cancer breakthroughs of 2011” by the Canadian Cancer Society. His lab also discovered that on exposure to low-frequency ultrasound, porphyrin microbubbles form nanoparticles that possess the same optical and therapeutic properties as the original microbubble, and can be used simultaneously for imaging and drug delivery (Nature Nano 2015). Dr. Zheng is an Associate Editor for Bioconjugate Chemistry and a Fellow of the American Institute for Medical and Biological Engineering. In 2019, he was awarded a Tier 1 Canada Research Chair in Cancer Nanomedicine.