Just six years since leaving Cambridge, Brianne Kent has secured a role as Assistant Professor, won multiple awards,  become the first early career researcher on the Governing Council of the Canadian Institutes of Health Research [CIHR] and is currently setting up her own laboratory to further her studies on Alzheimer’s disease. Since January, when she took up her Assistant Professorship and a…
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Antibiotics are used to treat bacterial infections by killing or inhibiting the growth of bacteria. However, bacteria can develop resistance to antibiotics, which each year accounts for at least 700,000 deaths worldwide. This is becoming an increasingly dangerous threat to society as resistance continues to rise globally. To prevent entering a post-antibiotic era, there have been extensive attempts to develop…
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Research Roundup: October 21, 2021

Inborn errors of immunity (IEIs) are a group of over 430 genetic disorders that result in a wide range of clinical manifestations such as increased susceptibility to infectious illness, autoinflammatory disease, allergy, and/or autoimmune conditions. Due to lack of awareness about IEIs among health care providers and due to the many ways IEIs can present, patients often experience long diagnostic…
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APEIRON Biologics AG, a privately held biotechnology company founded by LSI Director Dr. Josef Penninger has announced the start of a company-sponsored Phase 1 trial for inhalation of APN01. The double-blind, placebo-controlled, dose-escalation study plans to enroll about 40 healthy volunteers in Austria to assess the safety, tolerability, effects and performance of the drug, developed by Penninger in response to…
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Dani Evans was only nine years old when her 20/20 vision began to change radically. She used to sit in the back of the classroom, and could still see the board. The change to sitting in the front row, and having to take pictures she can zoom in on, came quickly. “It happened faster than the specialists thought it would,”…
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Understanding the dynamics within HIV transmission clusters is critical information that can help prioritize public health resource allocation. Although HIV sequence clustering is routinely used to identify subpopulations experiencing elevated transmission, there’s a risk of over-simplifying transmission dynamics within clusters as well as the risk that clustering methodology influences outcomes. In a newly published study written by BC-CfE researchers, led…
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A stacked lineup of industry vets from Eli Lilly, Versant, Amgen and more is teaming up to advance the field of multifunctional biotherapeutics. The seasoned executive team is launching Tentarix Biotherapeutics with the help of $50 million in series A fundraising. Co-led by Versant Ventures and Samsara BioCapital, the financing will help the team develop programs for oncology and autoimmune…
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Congratulations to Kevin Hay (Hay Lab) for receiving a Cell Therapy and Transplant Canada Hans Messner Award for his project entitled, “Cell-free DNA: A new biomarker in CAR-T cell therapy”. The funds received from this award will support a correlative study on the clinical trial Canadian-Led Immunotherapies in Cancer: CLIC-1901 for the Treatment of Patients with Relapsed/Refractory CD19 Positive Hematologic Malignancies, to…
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Congratulations to Pamela Hoodless (Hoodless Lab) for receiving a Cancer Research Society Operating Grant for her project entitled, “Defining epigenetic alterations in liver cancer at single cell resolution”. This research focuses on exploring how epigenetic networks are altered in hepatocellular carcinoma (HCC) compared to normal liver and how these alternation drive transcriptional changes. This work will further explore the alterations…
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