Publications of the Week Loss of Interruption in the HTT CAG Repeat Is Associated With Somatic Expansion and Loss of Medium Spiny Neurons in Huntington’s Disease Kay, C., et al. | September 23, 2026 Synonymous loss-of-interruption variants in the expanded CAG repeat sequence of Huntingtin (HTT) accelerate the clinical…karnottSeptember 23, 2026 Read More
Publications of the Week Protocol for Induction and Quantification of Injury-Primed Axon Outgrowth in Adult Mouse DRG Neurons Seburn, E., et al. | September 18, 2026 Adult dorsal root ganglion (DRG) neurons provide a powerful model to study axon growth. Dissociated…karnottSeptember 18, 2026 Read More
Publications of the Week Gestational Inhibition of CSF1R Signaling Using PLX5622 Drives Musculoskeletal Changes in Postnatal Offspring Memar, R., et al. | September 8, 2026 Despite our understanding of the musculoskeletal system under homeostatic conditions and during tissue remodeling, the…karnottSeptember 8, 2026 Read More
Publications of the Week A Microglia–Astrocyte Signaling Axis Regulates Astrocyte Piezo1 Expression and Inflammatory Responses Bai, Y., et al. | September 2, 2026 Structural tissue alterations in numerous brain disorders can initiate mechanosensory signaling pathways and influence neuropathology.…karnottSeptember 2, 2026 Read More
Publications of the Week Microbiome-Driven Alterations in Tryptophan Metabolism Contribute to Behavioral Comorbidities in the MUC2 Knockout Mouse Model of Chronic Colitis Josephson, J., et al. | August 21, 2026 Globally, the incidence of inflammatory bowel disease (IBD) is projected to reach 0.5% of the…karnottAugust 21, 2026 Read More
Publications of the Week Single-Cell Sequencing Unveils a Profibrotic Macrophage and Infiltrating Monocyte Niche in the Bronchoalveolar Lavage of Patients with Chronic Obstructive Pulmonary Disease Gerayeli, F., et al. | August 13, 2026 Chronic obstructive pulmonary disease (COPD) is characterized by global immune dysregulation. The most abundant immune…karnottAugust 13, 2026 Read More
Publications of the Week Population-Specific Heterogeneity in Ontogeny of the Broadly-Conserved Blood Transcriptional Program During the First Week of Life Dhillon, B., et al. | August 4, 2026 Previous research has shown that immune development during the first week of life, i.e. ontogeny,…karnottAugust 4, 2026 Read More
Publications of the Week Functional Segregation in Parkinson’s Disease Su, D., et al. | July 27, 2026 The basal ganglia are characterized by somatotopic representation and are organized in parallel, functionally segregated…karnottJuly 27, 2026 Read More
Publications of the Week A Binary Self-Amplifying Expression Platform Enabling Lipid Nanoparticle-Free Vaccines and Nanomedicines Jefferies, W., et al. | July 20, 2026 Conventional mRNA vaccines played a crucial role in mitigating the COVID-19 pandemic but remain hampered…karnottJuly 20, 2026 Read More
Publications of the Week Germline CDK12 Variants in Aggressive Prostate Cancer Tolmeijer, S., et al. | July 14, 2026 CDK12 mutations occur in 2-7% of metastatic prostate cancers (mPCa) and are considered to be…karnottJuly 14, 2026 Read More