Publications of the Week Neonatal Lipopolysaccharide Has Long-Term Effects on Steroids and Gene Expression in the Adult Mouse BrainBajaj, H., et al. | April 7, 2026Early-life infections can exert profound and lasting effects on brain development and function, potentially through…karnottApril 7, 2026 Read More
Publications of the Week Chemogenetic Inhibition of Developmentally-Born Hippocampal Neurons But Not Loss of Adult Neurogenesis Impairs Spatial Working Memory in the RatWard, M., et al. | April 3, 2026The dentate gyrus (DG) of the hippocampus contains a heterogeneous population of granule cells, being…karnottApril 3, 2026 Read More
Publications of the Week Prospective Multicenter Study of ctDNA Versus Tumor Tissue Guiding FGFR-Targeted Therapy in Metastatic Urothelial CancerMüller, D., et al. | March 25, 2026Fibroblast growth factor receptor (FGFR) alterations are targetable in metastatic urothelial carcinoma (mUC). Identifying FGFR…karnottMarch 25, 2026 Read More
Publications of the Week A Long Noncoding RNA–Based Classifier for Identifying More Aggressive Low-Grade Ta Bladder Cancer with Elevated FGFR3 ActivityPhung, T., et al. | March 20, 2026Low-grade, stage Ta (TaLG) non–muscle-invasive bladder cancer (NMIBC) is generally nonaggressive; yet, some patients experience…karnottMarch 20, 2026 Read More
Publications of the Week Self-Multimerization of mRNA LNP-Derived Antigen Improves Antibody ResponsesDespins, C., et al. | March 12, 2026Background: mRNA LNP technology is now being widely applied as a highly effective vaccine platform.…karnottMarch 12, 2026 Read More
Publications of the Week Formulation and Administration Timing of Lipid Derivatized JAK-Inhibitor and Corticosteroid Modulate saRNA-LNP Inflammation and ExpressionBathula, N., et al. | March 6, 2026Self-amplifying RNA (saRNA)-lipid nanoparticle (LNP) therapeutics represent a transformative advance in nucleic acid medicine, enabling…karnottMarch 6, 2026 Read More
Publications of the Week Silencing of Human HTT by Targeted CRISPR/dCas9-Mediated Epigenetic EditingTay, Y., et al. | February 23, 2026Gene silencing is widely recognized as a promising therapeutic approach for dominant monogenic disorders. Current…karnottFebruary 23, 2026 Read More
Publications of the Week Clonal Hematopoiesis After 177Lu-PSMA-617 Radioligand Therapy in Prostate CancerMunzur, A., et al. | February 20, 2026Background: Clonal hematopoiesis (CH) is a precursor state linked to risk of hematological neoplasms, and…karnottFebruary 20, 2026 Read More
Publications of the Week Direct Measurement of Free Glucocorticoids in Small Volumes of Mouse and Rat Serum Using Ultrafiltration and Liquid Chromatography-Tandem Mass SpectrometryMazurenko, A., et al. | February 17, 2026Glucocorticoids are critical steroid hormones secreted from the adrenal glands. In mice and rats, over…karnottFebruary 17, 2026 Read More
Publications of the Week Multidimensional Characterization of Tumour–Immune Architecture Reveals Clinically Relevant Classic Hodgkin Lymphoma SubtypesAoki, T., et al. | February 12, 2026The tissue architecture of classic Hodgkin Lymphoma (CHL) is unique among cancers and characterized by…karnottFebruary 12, 2026 Read More