Publications of the Week Single-Cell Spatial Atlas of the Aging Human BreastGupta, P., et al. | June 1, 2026Breast cancer can develop over a wide age range and tumors in younger women differ…karnottJune 1, 2026 Read More
Publications of the Week Reproducible Detection of Antigen-Specific T Cells and Tregs via Standardized and Automated Activation-Induced Marker Assay WorkflowsHalvorson, T., et al. | May 29, 2026Reliable detection of antigen-specific T cells is critical to understand immune responses to infection and…karnottMay 29, 2026 Read More
Publications of the Week Toward Multi(radio)metalated DNA: Enzymatic Polymerization of Metal-Chelate-Modified Deoxyribonucleoside TriphosphatesWong, A., et al. | May 20, 2026We report the first enzymatic synthesis of precisely defined metal-oligonucleotide conjugates through template-directed polymerase-mediated primer…karnottMay 20, 2026 Read More
Publications of the Week TMPRSS2 Inhibitors With Broad-Spectrum Efficacy Against SARS-CoV-2 (JN.1) and Influenza A (H1N1) Viruses Protect Mice From Influenza A InfectionPresley, L., et al. | May 13, 2026Human TMPRSS2 is a type II transmembrane serine protease and an essential host factor for…karnottMay 13, 2026 Read More
Publications of the Week IL1RAP Antibody-Drug Conjugates Potently Target Primary and Metastatic Disease in Multiple Oncofusion-Driven CancersZhang, H., et al. | May 4, 2026Gene fusions generated by chromosomal rearrangements function as oncogenic drivers in human cancers. We previously…karnottMay 4, 2026 Read More
Publications of the Week Drugging the Intrinsically Disordered Transactivation Domain of Androgen ReceptorObst, J., et al. | April 30, 2026Androgen receptor (AR) is a therapeutic target for prostate cancer. Despite effectively targeting its folded…karnottApril 30, 2026 Read More
Publications of the Week Single-Cell Spatial Atlas of the Aging Human BreastGupta, P., et al. | April 27, 2026Breast cancer can develop over a wide age range and tumors in younger women differ…karnottApril 27, 2026 Read More
Publications of the Week Noncanonical Functions of UGT2B17 Promote Castration-Resistant Prostate Cancer ProgressionFeng, T., et al. | April 20, 2026Androgen deprivation therapy is the primary treatment for advanced prostate tumors. While initially effective, tumor…karnottApril 20, 2026 Read More
Publications of the Week CSF1R+ Macrophage and Osteoclast Depletion Impairs Neural Crest Proliferation and Craniofacial MorphogenesisMa, F., et al. | April 16, 2026Despite a wealth of knowledge on the mechanisms underlying craniofacial morphogenesis during gestation, the roles…karnottApril 16, 2026 Read More
Publications of the Week Neonatal Lipopolysaccharide Has Long-Term Effects on Steroids and Gene Expression in the Adult Mouse BrainBajaj, H., et al. | April 7, 2026Early-life infections can exert profound and lasting effects on brain development and function, potentially through…karnottApril 7, 2026 Read More