Publications of the Week Microbiome-Driven Alterations in Tryptophan Metabolism Contribute to Behavioral Comorbidities in the MUC2 Knockout Mouse Model of Chronic Colitis Josephson, J., et al. | August 21, 2026 Globally, the incidence of inflammatory bowel disease (IBD) is projected to reach 0.5% of the…karnottAugust 21, 2026 Read More
Publications of the Week Single-Cell Sequencing Unveils a Profibrotic Macrophage and Infiltrating Monocyte Niche in the Bronchoalveolar Lavage of Patients with Chronic Obstructive Pulmonary Disease Gerayeli, F., et al. | August 13, 2026 Chronic obstructive pulmonary disease (COPD) is characterized by global immune dysregulation. The most abundant immune…karnottAugust 13, 2026 Read More
Publications of the Week Population-Specific Heterogeneity in Ontogeny of the Broadly-Conserved Blood Transcriptional Program During the First Week of Life Dhillon, B., et al. | August 4, 2026 Previous research has shown that immune development during the first week of life, i.e. ontogeny,…karnottAugust 4, 2026 Read More
Publications of the Week Functional Segregation in Parkinson’s Disease Su, D., et al. | July 27, 2026 The basal ganglia are characterized by somatotopic representation and are organized in parallel, functionally segregated…karnottJuly 27, 2026 Read More
Publications of the Week A Binary Self-Amplifying Expression Platform Enabling Lipid Nanoparticle-Free Vaccines and Nanomedicines Jefferies, W., et al. | July 20, 2026 Conventional mRNA vaccines played a crucial role in mitigating the COVID-19 pandemic but remain hampered…karnottJuly 20, 2026 Read More
Publications of the Week Germline CDK12 Variants in Aggressive Prostate Cancer Tolmeijer, S., et al. | July 14, 2026 CDK12 mutations occur in 2-7% of metastatic prostate cancers (mPCa) and are considered to be…karnottJuly 14, 2026 Read More
Publications of the Week Interval Positive Fecal Immunochemical Test is Associated with Postcolonoscopy Colorectal Cancer in a Screening Program Telford, J., et al. | July 7, 2026 Optimal management of individuals who have an unplanned, positive fecal immunochemical test after colonoscopy before…karnottJuly 7, 2026 Read More
Publications of the Week FAS-Controlled T Cells Drive Lymphoproliferation Through Glycolysis Without Effector Differentiation Maccari, M., et al. | July 3, 2026 Lymphoproliferation in autoimmune lymphoproliferative syndrome (ALPS) due to FAS deficiency is driven by highly proliferative…karnottJuly 3, 2026 Read More
Publications of the Week Saccharomycetes and Malassezia Fungi Associate With Early-Life Gut Maturation and Allergic Disease Risk in Childhood Hoskinson, C., et al. | July 3, 2026 While early-life gut bacterial microbiota maturation has been well studied and linked to childhood disease,…karnottJuly 3, 2026 Read More
Publications of the Week Human Germline Biallelic Loss-Of-Function OSMR Variants Cause Severe Allergic Disease Samra, S., et al. | June 25, 2026 Oncostatin M (OSM) receptor beta (OSMRβ), encoded by OSMR, is a cytokine receptor subunit required…karnottJune 25, 2026 Read More