As in several other scientific disciplines, pharmaceutical sciences, and in particularly nanomedicine is experiencing a reproducibility crisis [1]. This crisis has multiples roots, and can be in part explained by the use of ever more complex experimental protocols and specialized systems [2], inaccurate or incomplete description of methods employed and lack of rigor in the design of experimental plan.  However, another aspect that should not be ignored, and that possibly contributes to exacerbating this problem is the drift which is currently occurring in the publication practices, where for some groups, sharing scientific findings ceases to be the primary reason for publishing their research findings. Using examples taken mainly from the field of drug delivery, this presentation aims at analyzing the subtle causes that may contribute to the lack of reproducibility of the scientific literature and its impact on the society. It will also provide some possible solutions to disseminate new knowledge in a more reliable fashion.

References:

[1]. Leroux JC, Angew. Chem. Int. Ed. 2017, 56, 15170-15171.

[2]. Leroux JC, J Control. Release 2018, 278, 140-141.