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New PI Focus: Dr. Jennifer Ritonja Advances Research on Women’s Cancer Prevention

By October 27, 2025No Comments

When Dr. Jennifer Ritonja joined BC Cancer in July 2025 as a scientist, she set out to advance how we detect and prevent cancer in women. A trained epidemiologist, her research focuses on identifying early indicators of cancer in women, particularly for breast and ovarian cancers.

As part of this work, Dr. Ritonja studies the epigenetic changes, or chemical changes to a person’s body that can affect how their genes function, to help predict who may be at higher risk of developing cancer. She also examines life-course factors, exploring how a women’s cancer risk can change over time. Her research has shown that physical activity during key life stages, such as early to mid-adulthood years, can significantly affect ovarian cancer risk. Her findings also show that higher activity levels during those years appear to be protective against cancer.

Dr. Ritonja is a recipient of the Cancer Research Society’s Next Generation Scientist Award, which supports her study on mammographic breast density – the strongest breast cancer risk factor aside from genetics. Collaborating with BC Cancer researchers Dr. Parveen Bhatti, Dr. Charlotte Yong-Hing and Dr. Rasika Rajapakshe, she is investigating how changes in breast density over a woman’s life may better predict her future cancer risk.

“Rather than looking at breast density at a single point in time, we’re following how it changes across a woman’s life,” says Dr. Ritonja. “The goal is to improve breast screening guidelines and strengthen cancer risk prediction.”

Dr. Ritonja’s interest in women’s cancers began during her master’s studies at Queen’s University, where she became fascinated by cancers influenced by sex hormones.