Publications of the Week Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors Krentz, N.A.J., et al. | January 2, 2019 Human embryonic stem cells (hESCs) are a potential unlimited source of insulin-producing β cells for…sciencecityJanuary 2, 2019 Read More
Publications of the Week Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma Ennishi, D., et al. | December 14, 2018 Purpose High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-DH/TH) has a poor outcome after standard chemoimmunotherapy. We sought…sciencecityDecember 14, 2018 Read More
Publications of the Week IL-13 Signaling through IL-13 Receptor α2 Mediates Airway Epithelial Wound Repair Yang, S. J., et al. | December 13, 2018 The results presented in this manuscript demonstrate the role for the IL13 receptor Rα2 in…sciencecityDecember 13, 2018 Read More
Publications of the Week IVIg and LPS Co-Stimulation Induces IL-10 Production by Human Monocytes, which Is Compromised by an FcγRIIA Disease-Associated Gene Variant Kozicky, L.K., et al. | December 6, 2018 Intravenous Immunoglobulin (IVIg) is used to treat autoimmune or inflammatory diseases, but its mechanism of…sciencecityDecember 6, 2018 Read More
Publications of the Week Cellular Metabolism Constrains Innate Immune Responses in Early Human Ontogeny Kan, B., et al. | December 3, 2018 We have known for many years that these first-line responses, which are crucial to fight…sciencecityDecember 3, 2018 Read More
Publications of the Week Identification of a Novel Caspase Cleavage Site in Huntingtin that Regulates Mutant Huntingtin Clearance Martin, D.D.O., et al. | November 30, 2018 A caspase-1 inhibitor was shown to decrease not only caspase-1-mediated cleavage of HTT at 572,…sciencecityNovember 30, 2018 Read More
Publications of the Week Sources of Erroneous Sequences and Artifact Chimeric Reads in Next Generation Sequencing of Genomic DNA From Formalin-Fixed Paraffin-Embedded Samples Haile, S., et al. | November 26, 2018 Millions of clinical specimens are stored in the form of formalin-fixed paraffin-embedded (FFPE) samples. The…sciencecityNovember 26, 2018 Read More
Publications of the Week A Genome-Wide Screen Identifies Genes in Rhizosphere-Associated Pseudomonas Required to Evade Plant Defenses Liu, Z., et al. | November 22, 2018 Plant-associated microbial communities improve plant health by helping plants defend against pathogens and helping with…sciencecityNovember 22, 2018 Read More
Publications of the Week Granzyme K Expressed by Classically Activated Macrophages Contributes to Inflammation and Impaired Remodeling Turner, C.T., et al. | November 19, 2018 Granzyme K (GzmK) is occasionally referred to as an ‘orphan granzyme’ due to the lack…sciencecityNovember 19, 2018 Read More
Publications of the Week A Prospective Analysis of Human Leukemogenesis Eaves, C.J. | November 16, 2018 Decades of lack of progress in treating many fatal malignancies of the blood-forming system is…sciencecityNovember 16, 2018 Read More