Publications of the Week Gentamicin B1 Is a Minor Gentamicin Component with Major Nonsense Mutation Suppression ActivityBaradaran-Heravi, et al. | March 20, 2017ABSTRACT: Nonsense mutations underlie about 10% of rare genetic disease cases. They introduce a premature termination…sciencecityMarch 20, 2017 Read More
Publications of the Week 18F-Fluorination of Unactivated C–H Bonds in Branched Aliphatic Amino Acids: Direct Synthesis of Oncological Positron Emission Tomography Imaging AgentsNodwell, M.B. et al. | March 13, 2017ABSTRACT: A mild and selective photocatalytic C-H 18F-fluorination reaction has been developed that provides direct…sciencecityMarch 13, 2017 Read More
Publications of the Week CLK-Dependent Exon Recognition and Conjoined Gene Formation Revealed with a Novel Small Molecule InhibitorNature Communications | March 8, 2017ABSTRACT: CDC-like kinase phosphorylation of serine/arginine-rich proteins is central to RNA splicing reactions. Yet, the…sciencecityMarch 8, 2017 Read More
Publications of the Week CX-5461 is a DNA G-Quadruplex Stabilizer with Selective Lethality in BRCA1/2 Deficient TumoursXu, H. et al. | February 27, 2017ABSTRACT: G-quadruplex DNAs form four-stranded helical structures and are proposed to play key roles in different…sciencecityFebruary 27, 2017 Read More