Nearly 1 in 150 Canadians are infected with Hepatitis C (HCV). British Columbia has an even higher average, affecting nearly 1 in every 50 residents. While antiviral drugs can lead to effective cures in more than 90% of patients, their efficacy is challenged by drug resistant strains of the virus leading to viral relapse after therapy. Considering the extremely high…
An avid science enthusiast, Austin Wang began working in the laboratories of Dr. William Mohn, Dr. Susan Baldwin, and Dr. Steven Hallam at the University of British Columbia while still a student at David Thompson Secondary in Vancouver. In 2016, Austin traveled to Phoenix, Arizona to compete in the Intel International Science and Engineering Fair, taking home the grand prize…
This week, global experts will gather at the University of British Columbia to discuss the latest trends in 3D bioprinting—a technology used to create living tissues and organs. In this Q&A, UBC chemical and biological engineering professor Vikramaditya Yadav, who is also with the Regenerative Medicine Cluster Initiative in B.C., explains how bioprinting could potentially transform healthcare and drug development,…
PureTech Health plc (“PureTech Health” or the “Company”, LSE:PRTC), an advanced, clinical-stage biopharmaceutical company, is pleased to announce a licensing agreement between Commense, Inc. (“Commense”), a subsidiary of PureTech Health, and the University of British Columbia (“UBC”) for a microbiome-based therapy directed toward the prevention of asthma and other allergic diseases that present in childhood. This live biotherapeutic product bolsters…
We studied the whole-genome point mutation and structural variation patterns of 133 tumors (59 high-grade serous (HGSC), 35 clear cell (CCOC), 29 endometrioid (ENOC), and 10 adult granulosa cell (GCT)) as a substrate for class discovery in ovarian cancer. Ab initio clustering of integrated point mutation and structural variation signatures identified seven subgroups both between and within histotypes. Prevalence of…
Leading HIV/AIDS researcher Julio Montaner is among a group of scientists, writers, doctors and researchers receiving a prestigious prize for brilliant work in fields including health sciences, engineering and humanities. The Argentine-Canadian is among five scholars awarded this year’s Killam Prize, which honours Canadian researchers and scientists whose lifetime of work has impacted Canadians and citizens around the world. Each…
Dr. Julio Montaner, Director of the BC Centre for Excellence in HIV/AIDS, is one of five winners of the $100 000 Killam Prize. Grants Winner Grant Link to Article Dr. Shannon Kolind MS Society of Canada Grant Read More Awards Winner Award Link to Article Dr. Julio Montaner Killam Prize Read More Dr. Kalina Christoff Wall Scholars Research Award Read…
Heparin is a natural anticoagulant that derives its name from the tissue it was first isolated from: hepar in Greek means liver. Listed in the WHO Model List of Essential Medicines, heparin has stood the test of time as one of the oldest drugs still employed in clinical treatment to reduce clotting. However, heparin use is not without consequence as…
During pancreatic development, proliferating pancreatic progenitors activate the proendocrine transcription factor neurogenin 3 (NEUROG3), exit the cell cycle, and differentiate into islet cells. The mechanisms that direct robust NEUROG3 expression within a subset of progenitor cells control the size of the endocrine population. Here we demonstrate that NEUROG3 is phosphorylated within the nucleus on serine 183, which catalyzes its hyperphosphorylation…
The federal science minister says universities aren’t doing the heavy lifting to appoint more female research chairs, so she wants to force their hands. On her way to give a speech Wednesday to university presidents in Montreal, Kirsty Duncan was handed the latest statistics on the number of men and women among applicants for new Canada Research Chair positions. “They’re…
