Join us to celebrate November 8th when Business in Vancouver and MacKay CEO Forums present the 2017 BC CEO Awards. Winning CEOs will be profiled in Business in Vancouver on October 10th and honoured at a gala dinner where each winner will share their leadership lessons to an audience of Vancouver’s business community.
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Death by HDAC Inhibition in Synovial Sarcoma Cells

In synovial sarcoma, there is a known oncogene, SS18-SSX, but we have no drugs that target it directly. We have found that SS18-SSX acts by changing the epigenome, and it does so by hijacking and redirecting the activity of enzymes that modify histones. We found that a histone deacetylase inhibitor, quisinostat, is able to reverse some of the oncogenes changes, break up the abnormal complexes it forms, and kills synovial sarcoma cells in vitro and in a new mouse...
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BC’s forest products industry faces major challenges due to global competition and the decline in demand for traditional products such as newsprint. At the same time, there is increasing demand across the entire economy for environmentally-sustainable biomaterials. One way to address both of these issues is by converting woody biomass, which includes lignin, to higher valued bioproducts such as renewable…
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The federal government is spending over $42 million on science and engineering at the University of British Columbia, Canada’s minister of defence announced Friday. Harjit Sajjan, who was speaking on behalf of Minister of Science Kirsty Duncan, said the money is going towards “fundamental” research. The money will be distributed through the Natural Sciences and Engineering Research Council of Canada’s…
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Nine UBC researchers have been awarded $23.4 million in funding through foundation grants from the Canadian Institutes of Health Research (CIHR). Their individual amounts range from approximately $500,000 to over $5 million. With a duration of five to seven years, the grants are primarily used to support long-term health research projects, as well as knowledge translation and mentorship of students and trainees.“It’s…
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Sepset Biosciences Initiates Multicenter Human Clinical Study for Sepsis Treatment

Marking World Sepsis Day, Sepset Biosciences Inc., announces the commencement of a multi-country, multi-center human clinical study that will validate and refine Sepset’s proprietary gene signature to quickly and accurately identify patients with sepsis. A spin-out of The Centre for Drug Research and Development (CDRD), Sepset Biosciences, is developing a novel rapid diagnostic test that will enable healthcare professionals to provide…
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A key challenge to traditional genome wide association studies (GWAS) is that many identified genetic variants lie outside the protein coding regions, hence their functions are difficult to determine. To address this challenge, we performed quantitative trait locus (QTL) analyses on one of the largest multi-omic datasets for brain tissues, which comprises gene expression, DNA methylation, and histone modification...
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Our paper reports an important regulatory relationship between occluding junctions and hematopoietic progenitors. We believe, based on the existing literature in the field, that such a relationship is a common conserved feature of many types of stem cells and that our results have important wide-ranging implications. Moreover, our data...
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A recent study by a prolific TFRI-funded team has demonstrated that disrupting ERG transcriptional activity is sufficient to suppress the major characteristics of ERG-transformed prostate cancers. The finding could help develop new therapeutic tools for men battling ERG-expressing metastatic castration-resistant prostate cancer. There are currently few agents targeting cancer metastasis, and the need to create new therapeutics for these patients…
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Dr. Julie Robillard Appointed Associate Director, National Core for Neuroethics

Effective September 1, Dr. Julie Robillard (pictured, right) has been appointed Associate Director of the National Core for Neuroethics. The National Core for Neuroethics is an interdisciplinary research group with a mission to protect and ensure public good by aligning innovations in the brain sciences with human values. Dr. Robillard’s research focus is on the experience of health care innovation in dementia…
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Win $500 USD towards your registration fee for a cell and gene therapy conference