A newly identified pathway has been piquing research interest around the world for its possible role in ALS. Recently, Canadian virologist Dr. Honglin Luo, in collaboration with her colleague Dr. Neil Cashman, discovered that an immune pathway known as cGAS-STING – a catchier abbreviation for cyclic GMP-AMP synthase-stimulator of interferon genes – is activated by mutations in the SOD1 gene,…
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Podcast host Krista Lamb interviews Dr. Brian Rodrigues to discuss his research into diabetes and the heart. Dr. Brian Rodrigues is a Professor in the Faculty of Pharmaceutical Sciences at the University of British Columbia. During diabetes, the heart switches to using fats exclusively as an energy supply. Dr. Rodrigues is interested in examining the mechanism of how fat fuels…
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May 2021 Award Winners

Dr. Florian Kuchenbauer (pictured) won Proteona's Single Cell Multiomics Grant for multiple myeloma, which includes $50,000 USD in Proteona’s ESCAPE™ multi-omic single cell analysis services to better understand how and why highly complex tumours respond to new and existing therapies. Find out which other Vancouver researchers won grants, awards, or scholarships in this month's award summary.
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SFU computing science professor Ghassan Hamarneh is using his medical imaging analysis expertise to help UBC researchers understand the role of caveolin-1 (CAV1) in certain cancer types. CAV1 is a protein associated with poor outcomes in aggressive breast and prostate cancer. It is also associated with tumor metastasis and tumor suppression, but it is unclear how CAV1 differentiates between these…
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Androgen receptor (AR) is critical to the initiation, growth, and progression of prostate cancer. Once activated, the AR binds to cis-regulatory enhancer elements on DNA that drive gene expression. Yet, there are 10–100× more binding sites than differentially expressed genes. It is unclear how or if these excess binding sites impact gene transcription. To characterize the regulatory logic of AR-mediated…
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In 2015 Genome BC, Genome Quebec, and Genome Canada funded a significant, large-scale project to develop genomic tools to address challenges in improved management and the re-evaluation of hatchery / wild interactions of Coho salmon. The interdisciplinary team of natural and social scientists sequenced the Coho salmon genome, documented the genetic diversity of thousands of individual fish and determined how…
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Piscine orthoreovirus (PRV) – which is associated with kidney and liver damage in Chinook salmon – is continually being transmitted between open-net salmon farms and wild juvenile Chinook salmon in British Columbia waters, according to a new genomics analysis published today in Science Advances. The collaborative study from the University of British Columbia (UBC) and the Strategic Salmon Health Initiative…
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Simon Fraser University researchers announced Friday they have validated a faster, cheaper COVID-19 test that could help kickstart the expansion of wider rapid testing. “This research offers a cheaper, faster alternative to the most reliable and sensitive test currently used worldwide without sacrificing sensitivity and reproducibility,” said Peter Unrau, a SFU molecular biology and biochemistry professor who led the team…
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SBME Interfaces Ep. 12: Dr. Ali Tehrani

In this episode, we interface with Dr. Ali Tehrani, Co-founder, President and CEO of Zymeworks Inc. on launching Zymeworks, the profound moment that inspired him to science, communicating on its behalf, self-reflection, the BC Biomedical ecosystem, leadership, and more. Dr. Tehrani is a co-founder of Zymeworks and has served as President and Chief Executive Officer, and as a member of…
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