Robin F.B. Turner and James M. Piret are the winners of the 2022 William F. Meggers Award, to be presented this fall at the SciX conference, which will be held October 2–7 at the Northern Kentucky Convention Center in Greater Cincinnati. The Meggers Award, from the Society for Applied Spectroscopy, is given to the authors of the outstanding paper appearing…
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Dr. Calvin Yip's lab is interested in understanding how cells establish and maintain its gene expression pattern. Eukaryotic genomics DNA exists in a DNA-protein complex known as chromatin. A key mechanism cells regulate chromatin structure and genome accessibility is through post translational modifications of the histone proteins that form the most basic unit of chromatin called the nucleosome.
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Spruce (gen. Picea) is a keystone tree, widespread in the boreal and mountain ecosystems of the Northern hemisphere. The species also play a fundamental role in the forest industry, a major contributor to the Canadian economy. Spruce genome sequences will help future conservation efforts in the face of climate change. Spruce giga-genomes: structurally similar yet distinctive with differentially expanding gene families and…
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The antimicrobial properties of silver have been used in medicine for thousands of years. Silver ions punch holes in bacteria and once inside they bind to DNA, putting critical functions at risk. But creating a silver-based coating to keep bacteria off medical devices has proven to be a formidable challenge. That’s why researchers at the University of British Columbia and Vancouver…
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UBC researchers are part of an international collaboration that has discovered how to control the stickiness of adhesive bandages using ultrasound waves and bubbles. The breakthrough findings, published in the journal Science, could lead to new advances in medical adhesives, especially in cases where adhesives are difficult to apply such as on wet skin. “We were surprised to find that by…
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Carolina Tropini, a fellow in CIFAR’s Humans & the Microbiome program, gives insights in studying the human microbiota, and the potential it holds in precision medicine In graduate school, Carolina Tropini originally wanted to stay as far away from studying bacteria as possible. “The work that I saw first hand was just people researching E. coli. And I thought, this system is…
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A study involving Centre for Blood Research and Canadian Blood Services researchers Dr. Narges Hadjesfandiari, research associate, and Dr. Dana Devine, chief scientist, is helping to answer questions about the effect of infusion pumps on red blood cells (RBC) and make it easier to evaluate the safety of these pumps for this use. Published in Transfusion, the Journal of AABB, this research…
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Accurate and efficient folding of nascent protein sequences into their native states requires support from the protein homeostasis network. Herein we probe which newly translated proteins are thermo-sensitive, making them susceptible to misfolding and aggregation under heat stress using pulse-SILAC mass spectrometry. We find a distinct group of proteins that is highly sensitive to this perturbation when newly synthesized but…
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As Canada Tackles its 7th COVID-19 Wave, Covid-19 research network CoVarr-Net funded 15 New Studies to examine solutions to Omicron and other variants. Dr. François Jean, lead of Pillar 10: Antiviral Strategies and Antiviral Therapeutics, has been designated Project Lead of “Therapeutic Approaches and Emerging Therapies for SARS-CoV-2 VOCs: Mono or Combination Therapy, Mechanisms, and Antiviral Resistance.” Dr. Natalie Strynadka, a Pillar 10…
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Science has a thoroughly global focus, exists within an interdisciplinary intellectual environment, and succeeds through collaborative work that reaches across borders, oceans, and time zones. Indeed, the multi-national, multi-disciplinary and inclusive character of 21st century research mirrors the most formidable challenges of our era, from global pandemics, such as the one we’ve all experienced since 2020, to climate change.
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"CRISPR-Cas