Publications of the Week

To survive, cells must respond to changing environmental conditions. One way that eukaryotic cells react…

The development of vascular networks in microfluidic chips is crucial for the long-term culture of…

No consensus strategies exist for prognosticating metastatic castration-resistant prostate cancer (mCRPC). Circulating tumor DNA fraction…

This week we profile a recent publication in Developmental Cell by Matthew Shannon (pictured, right)…

Approximately 2 in 5 Canadians will be diagnosed with cancer in their lifetime, and yet we…

Targeted-immunotherapies such as antibody-drug conjugates (ADC), chimeric antigen receptor (CAR) T cells or bispecific T-cell…

Antifibrinolytic drugs are used extensively for on-demand treatment of severe acute bleeding. Controlling fibrinolysis may…

We have previously demonstrated that type II ryanodine receptors (RyR2) tetramers can be rapidly rearranged…

In recent years, the field of antibody drug conjugates (ADCs) has seen a resurgence, largely…

Pediatric acute myeloid leukemia (pAML) is characterized by heterogeneous cellular composition, driver alterations and prognosis.…