Publications of the Week Metagenomic and Metatranscriptomic Analysis of Human Prostate Microbiota from Patients with Prostate Cancer Feng, Y., et al. | March 7, 2019 Prostate cancer (PCa) is the most common malignant neoplasm among men in many countries. Since…sciencecityMarch 7, 2019 Read More
Publications of the Week Association of a Placental Interleukin-6 Genetic Variant (rs1800796) with DNA Methylation, Gene Expression and Risk of Acute Chorioamnionitis Konwar, C., et al. | March 5, 2019 Background Acute chorioamnionitis (aCA), inflammation of the placenta and fetal membranes, is a frequently reported…sciencecityMarch 5, 2019 Read More
Publications of the Week Podocalyxin Is Required for Maintaining Blood–Brain Barrier Function During Acute Inflammation Cait, J., et al. | March 1, 2019 The blood-brain barrier (BBB) separates the brain from circulating blood and it is essential for…sciencecityMarch 1, 2019 Read More
Publications of the Week The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock Arora, H., et al. | February 25, 2019 The authors conducted a gene expression screen to identify genes controlling innate and adaptive immunity,…sciencecityFebruary 25, 2019 Read More
Publications of the Week Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition Ennishi, D., et al. | February 21, 2019 In their most current integrative genomics studies the authors discovered the genetic and molecular features…sciencecityFebruary 21, 2019 Read More
Publications of the Week A High-Throughput Protocol for Isolating Cell-Free Circulating Tumour DNA from Peripheral Blood Pandoh, P.K., et al. | February 19, 2019 Standard isolation of ctDNA involves the separation of plasma by centrifugation followed by column or…sciencecityFebruary 19, 2019 Read More
Publications of the Week Loss of CIC Promotes Mitotic Dysregulation and Chromosome Segregation Defects Chittaranjan, S., et al. | February 15, 2019 Background: CIC is a transcriptional repressor inactivated by loss-of-function mutations in several cancer types, including…sciencecityFebruary 15, 2019 Read More
Publications of the Week An Allosteric MALT1 Inhibitor Is a Molecular Corrector Rescuing Function in an Immunodeficient Patient Quancard, J., et al. | February 11, 2019 MALT1 is a cysteine protease with both proteolytic and scaffolding functions that are key for…sciencecityFebruary 11, 2019 Read More
Publications of the Week ONECUT2 Is a Driver of Neuroendocrine Prostate Cancer Guo, H., et al. | February 6, 2019 Neuroendocrine prostate cancer (NEPC), a lethal form of the disease, is characterized by loss of…sciencecityFebruary 6, 2019 Read More
Publications of the Week Endogenous Insulin Contributes to Pancreatic Cancer Development Zhang, A.M.Y., et al. | February 4, 2019 The incidence of many cancers continues to rise alongside the global obesity and type 2…sciencecityFebruary 4, 2019 Read More