Publications of the Week Loss of CIC Promotes Mitotic Dysregulation and Chromosome Segregation Defects Chittaranjan, S., et al. | February 15, 2019 Background: CIC is a transcriptional repressor inactivated by loss-of-function mutations in several cancer types, including…sciencecityFebruary 15, 2019 Read More
Publications of the Week An Allosteric MALT1 Inhibitor Is a Molecular Corrector Rescuing Function in an Immunodeficient Patient Quancard, J., et al. | February 11, 2019 MALT1 is a cysteine protease with both proteolytic and scaffolding functions that are key for…sciencecityFebruary 11, 2019 Read More
Publications of the Week ONECUT2 Is a Driver of Neuroendocrine Prostate Cancer Guo, H., et al. | February 6, 2019 Neuroendocrine prostate cancer (NEPC), a lethal form of the disease, is characterized by loss of…sciencecityFebruary 6, 2019 Read More
Publications of the Week Endogenous Insulin Contributes to Pancreatic Cancer Development Zhang, A.M.Y., et al. | February 4, 2019 The incidence of many cancers continues to rise alongside the global obesity and type 2…sciencecityFebruary 4, 2019 Read More
Publications of the Week Transcriptional Regulation of Normal Human Mammary Cell Heterogeneity and its Perturbation in Breast Cancer Pellacani, D., et al. | January 31, 2019 The mammary gland in adult women consists of biologically distinct cell types that differ in…sciencecityJanuary 31, 2019 Read More
Publications of the Week Recalibrating the Relevance of Adult Neurogenesis Snyder, J.S. | January 29, 2019 Animal work has revealed that immature neurons born in the adult dentate gyrus have key…sciencecityJanuary 29, 2019 Read More
Publications of the Week Circulating Tumour DNA Abundance and Potential Utility in De Novo Metastatic Prostate Cancer Vandekerkhove, G., et al. | January 28, 2019 Our research focus is the genomics of advanced prostate and bladder cancer. Utilizing a combination…sciencecityJanuary 28, 2019 Read More
Publications of the Week A Topological View of Human CD34+ Cell State Trajectories from Integrated Single-Cell Output and Proteomic Data Knapp, D.J.H.F., et al. | January 25, 2019 Recent advances in single-cell molecular analytical methods and clonal growth assays are enabling more refined…sciencecityJanuary 25, 2019 Read More
Publications of the Week Genome-Wide Discovery of Somatic Coding and Non-Coding Mutations in Pediatric Endemic and Sporadic Burkitt Lymphoma Grande, B.M., et al. | January 23, 2019 In addition to being the largest genomic study of paediatric Burkitt lymphoma (BL) to date,…sciencecityJanuary 23, 2019 Read More
Publications of the Week Ionic Stress Enhances ER-PM Connectivity via Phosphoinositide-Associated SYT1 Contact Site Expansion in Arabidopsis Lee, E., et al. | January 21, 2019 In this publication we explain the long-term effect of salt stress in the proteins that…sciencecityJanuary 21, 2019 Read More