Publications of the Week Structural Insight into YcbB-Mediated Beta-Lactam Resistance in Escherichia Coli Caveney, N.A., et al. | May 6, 2019 In Escherichia coli, the peptidoglycan crosslinking reaction to form the cell wall is primarily carried…sciencecityMay 6, 2019 Read More
Publications of the Week Ibrutinib Displays Atrial-Specific Toxicity in Human Stem Cell-Derived Cardiomyocytes Shafaattalab, S., et al. | May 3, 2019 Ibrutinib (IB) is an oral Bruton's tyrosine kinase (BTK) inhibitor that has demonstrated benefit in…sciencecityMay 3, 2019 Read More
Publications of the Week Fusion-Dependent Formation of Lipid Nanoparticles Containing Macromolecular Payloads Kulkarni, J., et al. | April 29, 2019 Previous work from this group has suggested that the structure of lipid nanoparticles (LNPs) contained…sciencecityApril 29, 2019 Read More
Publications of the Week Particle Depletion Does Not Remediate Acute Effects of Traffic-Related Air Pollution and Allergen: A Randomized, Double-Blinded Crossover Study Wooding, D.J., et al. | April 25, 2019 Rationale: Diesel exhaust (DE), an established model of traffic-related air pollution, contributes significantly to the…sciencecityApril 25, 2019 Read More
Publications of the Week Evaluating Measures of Association for Single-Cell Transcriptomics Skinnider, M.A., et al. | April 23, 2019 Single-cell transcriptomics provides an opportunity to characterize cell-type-specific transcriptional networks, intercellular signaling pathways and cellular…sciencecityApril 23, 2019 Read More
Publications of the Week Splicing, Genome Stability and Disease: Splice Like Your Genome Depends on It! Tam, A.S. and Stirling, P.C. | April 18, 2019 The spliceosome has been implicated in genome maintenance for decades. Recently, a surge in discoveries…sciencecityApril 18, 2019 Read More
Publications of the Week Multi-Platform Discovery of Haplotype-Resolved Structural Variation in Human Genomes Chaisson, M.J.P., et al. | April 16, 2019 This the most detailed study to date describing differences between human genomes. The findings are…sciencecityApril 16, 2019 Read More
Publications of the Week A Widespread Coral-Infecting Apicomplexan with Chlorophyll Biosynthesis Genes Kwong, W., et al. | April 15, 2019 The authors show that the majority of corals worldwide harbor an intracellular microbe, which they…sciencecityApril 15, 2019 Read More
Publications of the Week HNF4A Is Essential for the Active Epigenetic State at Enhancers in Mouse Liver Thakur, A., et al. | April 12, 2019 Cell fate determination is influenced by interactions between master transcription factors (TFs) and cis‐regulatory elements.…sciencecityApril 12, 2019 Read More
Publications of the Week RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression Li, Y., et al. | April 10, 2019 This study defines the molecular mechanism by which the RNA splicing factor SRRM4 modulates RNA…sciencecityApril 10, 2019 Read More