Publications of the Week A Positive Feedback Loop between Myc and Aerobic Glycolysis Sustains Tumour Growth in a Drosophila Tumour Model Wong, K.K.L., et al. | July 8, 2019 Cancer cells usually exhibit aberrant cell signaling and metabolic reprogramming. However, mechanisms of crosstalk between…sciencecityJuly 8, 2019 Read More
Publications of the Week Neuroprotective Effect of CuATSM on Neurotoxin-Induced Motor Neuron Loss in an ALS Mouse Model Kuo, M.T.H., et al. | July 5, 2019 CuATSM, a copper homeostasis regulating compound, has been used as a PET-imaging agent for hypoxic…sciencecityJuly 5, 2019 Read More
Publications of the Week Specific Loss of Adipocyte CD248 Improves Metabolic Health via Reduced White Adipose Tissue Hypoxia, Fibrosis and Inflammation Petrus, P., et al. | July 3, 2019 Read the Publication This week we profile a recent publication in EBioMedicine from the laboratory…sciencecityJuly 3, 2019 Read More
Publications of the Week Therapeutic Implication of Genomic Landscape of Adult Metastatic Sarcoma Feng, X., et al. | June 28, 2019 PURPOSE This study investigated therapeutic potential of integrated genome and transcriptome profiling of metastatic sarcoma,…sciencecityJune 28, 2019 Read More
Publications of the Week Fixation Effects on Variant Calling in a Clinical Resequencing Panel Parker, J.D.K., et al. | June 27, 2019 Formalin fixation is the standard method for the preservation of tissue for diagnostic purposes, including…sciencecityJune 27, 2019 Read More
Publications of the Week Proteomic Profiling to Identify Blood Biomarkers Predictive of Response to Azithromycin in Children and Adolescents with Cystic Fibrosis Dong, K., et al. | June 25, 2019 Abstract Background Azithromycin reduces pulmonary exacerbation (PEx) risk in cystic fibrosis (CF) but not all…sciencecityJune 25, 2019 Read More
Publications of the Week Polycomb Contraction Differentially Regulates Terminal Human Hematopoietic Differentiation Programs Lorzadeh, A., et al. | June 20, 2019 Mature blood cells derive from primitive cells through a complex and poorly understood process that…sciencecityJune 20, 2019 Read More
Publications of the Week Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia Bernier, L.P., et al. | June 17, 2019 Microglia are highly ramified cells that constantly extend and retract processes to probe their environment…sciencecityJune 17, 2019 Read More
Publications of the Week An Enzymatic Pathway in the Human Gut Microbiome that Converts A to Universal O Type Blood Rahfeld, P., et al | June 13, 2019 The Withers lab has been interested in using the technique of metagenomics to discover new…sciencecityJune 13, 2019 Read More
Publications of the Week Exome Sequencing in Multiple Sclerosis Families Identifies 12 Candidate Genes and Nominates Biological Pathways for the Genesis of Disease Vilariño-Güell, C., et al. | June 10, 2019 Most treatments for multiple sclerosis (MS) target the adaptive immune and may ameliorate the patients’…sciencecityJune 10, 2019 Read More