Publications of the Week Polycomb Contraction Differentially Regulates Terminal Human Hematopoietic Differentiation Programs Lorzadeh, A., et al. | June 20, 2019 Mature blood cells derive from primitive cells through a complex and poorly understood process that…sciencecityJune 20, 2019 Read More
Publications of the Week Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia Bernier, L.P., et al. | June 17, 2019 Microglia are highly ramified cells that constantly extend and retract processes to probe their environment…sciencecityJune 17, 2019 Read More
Publications of the Week An Enzymatic Pathway in the Human Gut Microbiome that Converts A to Universal O Type Blood Rahfeld, P., et al | June 13, 2019 The Withers lab has been interested in using the technique of metagenomics to discover new…sciencecityJune 13, 2019 Read More
Publications of the Week Exome Sequencing in Multiple Sclerosis Families Identifies 12 Candidate Genes and Nominates Biological Pathways for the Genesis of Disease Vilariño-Güell, C., et al. | June 10, 2019 Most treatments for multiple sclerosis (MS) target the adaptive immune and may ameliorate the patients’…sciencecityJune 10, 2019 Read More
Publications of the Week Length of Uninterrupted CAG, Independent of Polyglutamine Size, Results in Increased Somatic Instability, Hastening Onset of Huntington Disease Wright, G.E.B., et al. | June 7, 2019 This study focuses on the area surrounding a pathogenic polyglutamine repeat in patients with Huntington…sciencecityJune 7, 2019 Read More
Publications of the Week Stress-Induced Tunneling Nanotubes Support Treatment Adaptation in Prostate Cancer Kretschmer, A., et al. | June 4, 2019 Tunneling nanotubes (TNTs) are actin-based membranous structures bridging distant cells for intercellular communication. We define…sciencecityJune 4, 2019 Read More
Publications of the Week Characterization of Transcriptomic Signature of Primary Prostate Cancer Analogous to Prostatic Small Cell Neuroendocrine Carcinoma Alshalalfa, M., et al. | May 31, 2019 Prostatic small cell neuroendocrine carcinoma (SC/NE) is well studied in metastatic CRPC, however, it is…sciencecityMay 31, 2019 Read More
Publications of the Week ApoA-I Deficiency Increases Cortical Amyloid Deposition, Cerebral Amyloid Angiopathy, Cortical and Hippocampal Astrogliosis, and Amyloid-Associated Astrocyte Reactivity in APP/PS1 Mice Button, E.B., et al. | May 27, 2019 This publication shows that mice with low levels of high-density lipoproteins (HDL) (commonly known as…sciencecityMay 27, 2019 Read More
Publications of the Week Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signalling Coulombe, P., et al. | May 21, 2019 Lung immaturity is a major cause of respiratory distress and mortality in premature newborns. In…sciencecityMay 21, 2019 Read More
Publications of the Week Upregulation of Scavenger Receptor B1 Is Required for Steroidogenic and Non-Steroidogenic Cholesterol Metabolism in Prostate Cancer Gordon, J., et al. | May 20, 2019 Aberrant cholesterol metabolism is increasingly appreciated to be essential for prostate cancer (PCa) initiation and…sciencecityMay 20, 2019 Read More