Publications of the Week Endogenous Hyperinsulinemia Contributes to Pancreatic Cancer Development Zhang, A.M.Y., et al. | August 9, 2019 The incidence of cancers, including pancreatic ductal adenocarcinoma (PDAC), continues to rise alongside the global…sciencecityAugust 9, 2019 Read More
Publications of the Week Closed-Loop Optogenetic Activation of Peripheral or Central Neurons Modulates Feeding in Freely Moving Drosophila Musso, P., et al. | August 7, 2019 Manipulating feeding circuits in freely moving animals is challenging, in part because the timing of…sciencecityAugust 7, 2019 Read More
Publications of the Week Profiling the E. coli Membrane Interactome Captured in Peptidisc Libraries Carlson, M.L., et al. | August 6, 2019 The authors describe a new method - the peptidisc method - for reconstituting the E.…sciencecityAugust 6, 2019 Read More
Publications of the Week Modulation of Innate Immunity by Amyloidogenic Peptides Westwell-Roper, C. and Verchere C.B. | July 31, 2019 Amyloidogenic peptides of both bacterial and mammalian origin transition through multiple aggregation states with distinct…sciencecityJuly 31, 2019 Read More
Publications of the Week Gene Expression Profiles Complement the Analysis of Genomic Modifiers of the Clinical Onset of Huntington Disease Wright, G.E.B, et al. | July 29, 2019 In an attempt to identify genomic modifiers that contribute towards the age of onset of…sciencecityJuly 29, 2019 Read More
Publications of the Week Cryo-EM Structures Reveal Coordinated Domain Motions that Govern DNA Cleavage by Cas9 Zhu, X., et al. | July 25, 2019 The RNA-guided Cas9 endonuclease from Streptococcus pyogenes is a single-turnover enzyme that displays a stable product state…sciencecityJuly 25, 2019 Read More
Publications of the Week Transcriptional Regulation of Normal Human Mammary Cell Heterogeneity and Its Perturbation in Breast Cancer Pellacani, D., et al. | July 23, 2019 The mammary gland in adult women consists of biologically distinct cell types that differ in…sciencecityJuly 23, 2019 Read More
Publications of the Week New Insights into the Intrinsic and Extrinsic Factors that Shape the Human Skin Microbiome Dimitriu, P.A., et al. | July 19, 2019 Many studies have shown that body site and inter-personal differences shape the composition of the…sciencecityJuly 19, 2019 Read More
Publications of the Week Coding and Non-Coding Drivers of Mantle Cell Lymphoma Identified through Exome and Genome Sequencing Pararajalingam, P., et al. | July 18, 2019 Mantle cell lymphoma (MCL) is an uncommon B-cell non-Hodgkin lymphoma (NHL) that is incurable with…sciencecityJuly 18, 2019 Read More
Publications of the Week Synthetic Modeling Reveals HOXB Genes are Critical for the Initiation and Maintenance of Human Leukemia Kusakabe, M., et al. | July 12, 2019 In this manuscript, the authors describe a completely synthetic, efficient, and highly reproducible means for…sciencecityJuly 12, 2019 Read More