Publications of the Week Generation of Blood Vessel Organoids from Human Pluripotent Stem Cells Wimmer, R.A., et al. | October 9, 2019 The authors describe a method for the generation of blood vessel organoids from pluripotent stem…sciencecityOctober 9, 2019 Read More
Publications of the Week p97 Regulates GluA1 Homomeric AMPA Receptor Formation and Plasma Membrane Expression Ge, Y., et al. | October 4, 2019 The α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptors (AMPARs) mediate the fast excitatory synaptic transmission in the…sciencecityOctober 4, 2019 Read More
Publications of the Week Probabilistic Cell-Type Assignment of Single-Cell RNA-Seq for Tumour Microenvironment Profiling Zhang, A.W., et al. | October 2, 2019 Single-cell RNA sequencing has enabled the decomposition of complex tissues into functionally distinct cell types.…sciencecityOctober 2, 2019 Read More
Publications of the Week MRE11-RAD50-NBS1 Promotes Fanconi Anemia R-Loop Suppression at Transcription–Replication Conflicts Chang, E.Y., et al. | September 30, 2019 The authors found that a well-characterized DNA repair complex, called the MRN complex, had a…sciencecitySeptember 30, 2019 Read More
Publications of the Week Recent Advances in Lipid Nanoparticle-Mediated mRNA Therapy Maurer, N., & Kulkarni, J., | September 27, 2019 All cells function by an intricate mechanism that converts information stored as nucleic acid sequences…sciencecitySeptember 27, 2019 Read More
Publications of the Week Cryo-EM Structure of a Dimeric B-Raf:14-3-3 Complex Reveals Asymmetry in the Active Sites of B-Raf Kinases Kondo, Y., et al. | September 26, 2019 The authors identified the mechanism of action of B-Raf, a key enzyme that is mutated…sciencecitySeptember 26, 2019 Read More
Publications of the Week Suppressive and Gut Reparative Functions of Human Type 1 T-Regulatory Cells Cook, L., et al. | September 23, 2019 The authors found that type 1 T-regulatory (Tr1) cells have functions outside beyond their expected…sciencecitySeptember 23, 2019 Read More
Publications of the Week Targeting Myeloid-Derived Suppressor Cells in Combination with Primary Mammary Tumour Resection Reduces Metastatic Growth in the Lungs Bosiljcic, M., et al. | September 19, 2019 Solid tumors produce proteins that can induce the accumulation of bone marrow-derived cells in various…sciencecitySeptember 19, 2019 Read More
Publications of the Week Comprehensive Genomic Profiling of Glioblastoma Tumors, BTICs, and Xenografts Reveals Stability and Adaptation to Growth Environments Shen, Y., et al. | September 16, 2019 The authors employed expertise in DNA sequencing and analysis to characterize the genetics of tumour…sciencecitySeptember 16, 2019 Read More
Publications of the Week The Evolution of Long Noncoding RNA Acceptance in Prostate Cancer Initiation and Progression, and Its Clinical Utility in Disease Management Ramnarine, V.R., et al. | September 13, 2019 It is increasingly evident that non–protein-coding regions of the genome can give rise to transcripts…sciencecitySeptember 13, 2019 Read More