Publications of the Week Androgen Receptor Plasticity and Its Implications for Prostate Cancer Therapy Snow, O., et al. | November 20, 2019 Acquired resistance to a drug treatment is a common problem across many cancers including prostate…sciencecityNovember 20, 2019 Read More
Publications of the Week Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction Fenninger, F., et al. | November 15, 2019 In order to respond to foreign invaders and emerging cancers, specific cells of the immune…sciencecityNovember 15, 2019 Read More
Publications of the Week Biological Embedding of Experience: A Primer on Epigenetics Aristizabel, M.J., et al. | November 14, 2019 Biological embedding occurs when life experience alters biological processes to affect later life health and…sciencecityNovember 14, 2019 Read More
Publications of the Week Class I HDAC Inhibitors Enhance YB-1 Acetylation and Oxidative Stress to Block Sarcoma Metastasis El-Naggar, A.M., et al. | November 8, 2019 Outcomes for metastatic Ewing sarcoma and osteosarcoma are dismal and have not changed for decades.…sciencecityNovember 8, 2019 Read More
Publications of the Week Higher-Order Epistasis Shapes the Fitness Landscape of a Xenobiotic-Degrading Enzyme Yang, G., et al. | November 5, 2019 Characterizing the adaptive landscapes that encompass the emergence of novel enzyme functions can provide molecular…sciencecityNovember 5, 2019 Read More
Publications of the Week Long Non-Coding RNAs Identify a Subset of Luminal Muscle-Invasive Bladder Cancer Patients with Favorable Prognosis de Jong, J.J., et al. | October 31, 2019 Background Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease, and gene expression profiling has identified…sciencecityOctober 31, 2019 Read More
Publications of the Week Dissociation of Solid Tumor Tissues with Cold Active Protease for Single-Cell RNA-Seq Minimizes Conserved Collagenase-Associated Stress Responses O’Flanagan, C.H., et al. | October 28, 2019 Single-cell RNA sequencing (scRNA-seq) is a powerful tool for studying complex biological systems, such as…sciencecityOctober 28, 2019 Read More
Publications of the Week Diversity of Small Molecule HIV-1 Latency Reversing Agents Identified in Low- and High-Throughput Small Molecule Screens Hashemi, P., and Sadowski, I. | October 25, 2019 The latency phenomenon produced by human immunodeficiency virus (HIV‐1) prevents viral clearance by current therapies,…sciencecityOctober 25, 2019 Read More
Publications of the Week Discordance in the Epithelial Cell-Dendritic Cell MHC Class II Immunoproteome: Implications for Chlamydia Vaccine Development Karunakaran, K.P., et al. | October 23, 2019 Chlamydia trachomatis and C. muridarum are intracellular bacterial pathogens of mucosal epithelial cells. CD4 T cells and major…sciencecityOctober 23, 2019 Read More
Publications of the Week The PedBE Clock Accurately Estimates DNA Methylation Age in Pediatric Buccal Cells McEwen, L.M., et al | October 21, 2019 DNA methylation is the most studied modification in human population epigenetics. Its information content can…sciencecityOctober 21, 2019 Read More