Publications of the Week Identification of Hypermutation and Defective Mismatch Repair in ctDNA from Metastatic Prostate Cancer Ritch, E., et al. | December 5, 2019 It has been shown that metastatic prostate cancers with mismatch repair defects are likely to…sciencecityDecember 5, 2019 Read More
Publications of the Week The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation Shimell, J.J., et al. | December 3, 2019 Loss-of-function variants in ZDHHC9 have been identified in patients with X-linked intellectual disability (XLID), with…sciencecityDecember 3, 2019 Read More
Publications of the Week Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumour Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration Chun, H.E., et al. | November 29, 2019 The researchers conducted extensive analyses of the genomes, epigenomes and transcriptomes of Rhabdoid tumours (RTs)…sciencecityNovember 29, 2019 Read More
Publications of the Week Biodiversity of Protists and Nematodes in the Wild Nonhuman Primate Gut Mann, A., et al | November 28, 2019 Documenting the natural diversity of eukaryotic organisms in the nonhuman primate (NHP) gut is important…sciencecityNovember 28, 2019 Read More
Publications of the Week A Comprehensive Haplotype Targeting Strategy for Allele-Specific HTT Suppression in Huntington Disease Kay, C., et al. | November 25, 2019 In Huntington disease (HD), the mutated HTT gene expresses with pathogenic gain-of-function activities. The authors…sciencecityNovember 25, 2019 Read More
Publications of the Week Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity Jin, S.W., et al. | November 22, 2019 The cellular multipass transmembrane protein serine incorporator 5 (SERINC5) was recently identified to be a…sciencecityNovember 22, 2019 Read More
Publications of the Week Androgen Receptor Plasticity and Its Implications for Prostate Cancer Therapy Snow, O., et al. | November 20, 2019 Acquired resistance to a drug treatment is a common problem across many cancers including prostate…sciencecityNovember 20, 2019 Read More
Publications of the Week Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction Fenninger, F., et al. | November 15, 2019 In order to respond to foreign invaders and emerging cancers, specific cells of the immune…sciencecityNovember 15, 2019 Read More
Publications of the Week Biological Embedding of Experience: A Primer on Epigenetics Aristizabel, M.J., et al. | November 14, 2019 Biological embedding occurs when life experience alters biological processes to affect later life health and…sciencecityNovember 14, 2019 Read More
Publications of the Week Class I HDAC Inhibitors Enhance YB-1 Acetylation and Oxidative Stress to Block Sarcoma Metastasis El-Naggar, A.M., et al. | November 8, 2019 Outcomes for metastatic Ewing sarcoma and osteosarcoma are dismal and have not changed for decades.…sciencecityNovember 8, 2019 Read More