Publications of the Week Length of Uninterrupted CAG, Independent of Polyglutamine Size, Results in Increased Somatic Instability, Hastening Onset of Huntington Disease Wright, G.E.B., et al. | June 7, 2019 This study focuses on the area surrounding a pathogenic polyglutamine repeat in patients with Huntington…sciencecityJune 7, 2019 Read More
Publications of the Week Stress-Induced Tunneling Nanotubes Support Treatment Adaptation in Prostate Cancer Kretschmer, A., et al. | June 4, 2019 Tunneling nanotubes (TNTs) are actin-based membranous structures bridging distant cells for intercellular communication. We define…sciencecityJune 4, 2019 Read More
Publications of the Week Characterization of Transcriptomic Signature of Primary Prostate Cancer Analogous to Prostatic Small Cell Neuroendocrine Carcinoma Alshalalfa, M., et al. | May 31, 2019 Prostatic small cell neuroendocrine carcinoma (SC/NE) is well studied in metastatic CRPC, however, it is…sciencecityMay 31, 2019 Read More
Publications of the Week ApoA-I Deficiency Increases Cortical Amyloid Deposition, Cerebral Amyloid Angiopathy, Cortical and Hippocampal Astrogliosis, and Amyloid-Associated Astrocyte Reactivity in APP/PS1 Mice Button, E.B., et al. | May 27, 2019 This publication shows that mice with low levels of high-density lipoproteins (HDL) (commonly known as…sciencecityMay 27, 2019 Read More
Publications of the Week Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signalling Coulombe, P., et al. | May 21, 2019 Lung immaturity is a major cause of respiratory distress and mortality in premature newborns. In…sciencecityMay 21, 2019 Read More
Publications of the Week Upregulation of Scavenger Receptor B1 Is Required for Steroidogenic and Non-Steroidogenic Cholesterol Metabolism in Prostate Cancer Gordon, J., et al. | May 20, 2019 Aberrant cholesterol metabolism is increasingly appreciated to be essential for prostate cancer (PCa) initiation and…sciencecityMay 20, 2019 Read More
Publications of the Week Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor Caveney, N., et al. | May 15, 2019 Bacteria identify and respond to DNA damage using the SOS response. LexA, a central repressor…sciencecityMay 15, 2019 Read More
Publications of the Week The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in a Phosphorylation-Dependent Manner Haji-Ghassemi, O., et al. | May 13, 2019 The ryanodine receptor is a channel is of key importance in heart muscle contraction and…sciencecityMay 13, 2019 Read More
Publications of the Week Inhibition of GLI2 with Antisense-Oligonucleotides: A Potential Therapy for the Treatment of Bladder Cancer Raven, P.A., et al. | May 10, 2019 As a surgeon scientist, Dr. Alan So’s interest in research is to meld both bench…sciencecityMay 10, 2019 Read More
Publications of the Week Cancer Stemness, Intratumoral Heterogeneity, and Immune Response Across Cancers Miranda, A., et al. | May 8, 2019 Regulatory programs that control the function of stem cells are active in cancer and confer…sciencecityMay 8, 2019 Read More