Publications of the Week Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor Caveney, N., et al. | May 15, 2019 Bacteria identify and respond to DNA damage using the SOS response. LexA, a central repressor…sciencecityMay 15, 2019 Read More
Publications of the Week The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in a Phosphorylation-Dependent Manner Haji-Ghassemi, O., et al. | May 13, 2019 The ryanodine receptor is a channel is of key importance in heart muscle contraction and…sciencecityMay 13, 2019 Read More
Publications of the Week Inhibition of GLI2 with Antisense-Oligonucleotides: A Potential Therapy for the Treatment of Bladder Cancer Raven, P.A., et al. | May 10, 2019 As a surgeon scientist, Dr. Alan So’s interest in research is to meld both bench…sciencecityMay 10, 2019 Read More
Publications of the Week Cancer Stemness, Intratumoral Heterogeneity, and Immune Response Across Cancers Miranda, A., et al. | May 8, 2019 Regulatory programs that control the function of stem cells are active in cancer and confer…sciencecityMay 8, 2019 Read More
Publications of the Week Structural Insight into YcbB-Mediated Beta-Lactam Resistance in Escherichia Coli Caveney, N.A., et al. | May 6, 2019 In Escherichia coli, the peptidoglycan crosslinking reaction to form the cell wall is primarily carried…sciencecityMay 6, 2019 Read More
Publications of the Week Ibrutinib Displays Atrial-Specific Toxicity in Human Stem Cell-Derived Cardiomyocytes Shafaattalab, S., et al. | May 3, 2019 Ibrutinib (IB) is an oral Bruton's tyrosine kinase (BTK) inhibitor that has demonstrated benefit in…sciencecityMay 3, 2019 Read More
Publications of the Week Fusion-Dependent Formation of Lipid Nanoparticles Containing Macromolecular Payloads Kulkarni, J., et al. | April 29, 2019 Previous work from this group has suggested that the structure of lipid nanoparticles (LNPs) contained…sciencecityApril 29, 2019 Read More
Publications of the Week Particle Depletion Does Not Remediate Acute Effects of Traffic-Related Air Pollution and Allergen: A Randomized, Double-Blinded Crossover Study Wooding, D.J., et al. | April 25, 2019 Rationale: Diesel exhaust (DE), an established model of traffic-related air pollution, contributes significantly to the…sciencecityApril 25, 2019 Read More
Publications of the Week Evaluating Measures of Association for Single-Cell Transcriptomics Skinnider, M.A., et al. | April 23, 2019 Single-cell transcriptomics provides an opportunity to characterize cell-type-specific transcriptional networks, intercellular signaling pathways and cellular…sciencecityApril 23, 2019 Read More
Publications of the Week Splicing, Genome Stability and Disease: Splice Like Your Genome Depends on It! Tam, A.S. and Stirling, P.C. | April 18, 2019 The spliceosome has been implicated in genome maintenance for decades. Recently, a surge in discoveries…sciencecityApril 18, 2019 Read More