Publications of the Week SOX4 Allows Facultative β-Cell Proliferation Through Repression of Cdkn1aXu, E.E. and Lynn, F.C., et al. | May 31, 2017The Lynn Lab focuses on understanding the development, function and aging of insulin-producing pancreatic ß-cells…sciencecityMay 31, 2017 Read More
Publications of the Week Genetic Modifiers of Multiple Sclerosis Progression, Severity and OnsetSadovnick, A.D. and Vilarino-Guell, C., et al. | May 29, 2017The focus of our research is to discover pathogenic mutations leading to the onset of…sciencecityMay 29, 2017 Read More
Publications of the Week The Sunflower Genome Provides Insights into Oil Metabolism, Flowering and Asterid EvolutionRieseberg, L.H. and Langlade, N.B., et al. | May 24, 2017Read the Publication Vancouver, BC – Cultivated sunflowers are one of the five largest oilseed…sciencecityMay 24, 2017 Read More
Publications of the Week Assessment of the ExAC Data Set for the Presence of Individuals with Pathogenic Genotypes Implicated in Severe Mendelian Pediatric DisordersTarailo-Graovac, M. and Wasserman, W.W., et al. | May 22, 2017My laboratory is focused on the creation and application of computational software and methods for…sciencecityMay 22, 2017 Read More
Publications of the Week Single-Cell Template Strand Sequencing by Strand-Seq Enables the Characterization of Individual HomologsSanders, A.D. and Lansdorp, P.M., et al. | May 19, 2017My research is and has been focused on the role of genome instability in stem…sciencecityMay 19, 2017 Read More
Publications of the Week The Histone Methyltransferase EZH2 Is a Therapeutic Target in Small Cell Carcinoma of the Ovary, Hypercalcemic TypeWang, Y. and Huntsman, D.G., et al. | May 15, 2017Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare but extremely lethal…sciencecityMay 15, 2017 Read More
Publications of the Week Stat3 Regulates Centrosome Clustering in Cancer Cells via Stathmin/PLK1Morris, E.J. and Dedhar, S., et al. | May 15, 2017Cancer cells have been observed to frequently have amplified centrosomes. These amplified centrosomes must be…sciencecityMay 15, 2017 Read More
Publications of the Week Reappraisal of TDP-43 Pathology in FTLD-U SubtypesMackenzie, I.R., et al. | May 12, 2017Frontotemporal lobar degeneration with tau-negative, ubiquitin-immunoreactive (-ir) pathology (FTLD-U) is subclassified based on the type…sciencecityMay 12, 2017 Read More
Publications of the Week Genomic Consequences of Aberrant DNA Repair Mechanisms Stratify Ovarian Cancer HistotypesWang, Y.K. and Shah, S.P., et al. | May 8, 2017We studied the whole-genome point mutation and structural variation patterns of 133 tumors (59 high-grade…sciencecityMay 8, 2017 Read More
Publications of the Week Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic ProgenitorsKrentz, N. A. J. and Lynn, F.C., et al. | May 5, 2017During pancreatic development, proliferating pancreatic progenitors activate the proendocrine transcription factor neurogenin 3 (NEUROG3), exit…sciencecityMay 5, 2017 Read More