Publications of the Week STING Pathway Expression in Low-Grade Serous Carcinoma of the Ovary: An Unexpected Therapeutic Opportunity? Huvila, J., et al. | June 22, 2021 Ovarian carcinoma histotypes are distinct diseases with variable clinical outcomes and response to treatment. There…pthomsonJune 22, 2021 Read More
Publications of the Week Context-Aware Synthetic Biology by Controller Design: Engineering the Mammalian Cell Shakiba, N., & Jones, R. D., et al. | June 21, 2021 The rise of systems biology has ushered a new paradigm: the view of the cell…pthomsonJune 21, 2021 Read More
Publications of the Week Extracellular Signal-Regulated Kinase Mediates Chromatin Rewiring and Lineage Transformation in Lung Cancer Inoue, Y., et al. | June 18, 2021 Small-cell lung cancer (SCLC) is neuroendocrine in origin and rarely contains mutations in the MAPK…pthomsonJune 18, 2021 Read More
Publications of the Week Turmeric and Its Bioactive Constituents Trigger Cell Signalling Mechanisms That Protect against Diabetes and Cardiovascular Diseases Zhang, H. A. & Kitts, D. D. | June 16, 2021 Turmeric, the rhizome of Curcuma longa plant belonging to the ginger family Zingiberaceae, has a history in…pthomsonJune 16, 2021 Read More
Publications of the Week SARS-CoV-2 RNA Quantification Using Droplet Digital RT-PCR Kinloch, N. N., et al. | June 11, 2021 Quantitative viral load assays have transformed our understanding of viral diseases. They hold similar potential…pthomsonJune 11, 2021 Read More
Publications of the Week Epistasis and Intramolecular Networks in Protein Evolution Miton, C. M., et al. | June 8, 2021 Proteins are molecular machines composed of complex, highly connected amino acid networks. Their functional optimization…pthomsonJune 8, 2021 Read More
Publications of the Week Transcriptome-Wide Association Study Uncovers the Role of Essential Genes in Anthracycline-Induced Cardiotoxicity Scott, E. N., et al. | June 4, 2021 Anthracyclines are highly effective chemotherapeutic agents; however, their clinical utility is limited by severe anthracycline-induced…pthomsonJune 4, 2021 Read More
Publications of the Week CryoEM Structure of the Antibacterial Target PBP1b at 3.3 Å Resolution Caveney, N., et al. | May 31, 2021 This week we profile a recent publication in Nature Communications from Dr. Nathanael Caveney, Dr.…pthomsonMay 31, 2021 Read More
Publications of the Week Functional Mapping of Androgen Receptor Enhancer Activity Huang, C.-C. F., et al. | May 28, 2021 Androgen receptor (AR) is critical to the initiation, growth, and progression of prostate cancer. Once…pthomsonMay 28, 2021 Read More
Publications of the Week Induction of Stable Human FOXP3+ Tregs by a Parasite-Derived TGF-β Mimic Cook, L., et al. | May 25, 2021 This week we profile a recent publication in Immunology & Cell Biology from the laboratory…pthomsonMay 25, 2021 Read More