Publications of the Week Bone Morphogenetic Protein 2 Promotes Human Trophoblast Cell Invasion and Endothelial-Like Tube Formation through ID1-Mediated Upregulation of IGF Binding Protein-3Zhao, H.J., et al. | January 17, 2020Extravillous cytotrophoblasts (EVTs) invade into the uterine wall and remodel spiral arteries for proper placentation.…sciencecityJanuary 17, 2020 Read More
Publications of the Week Cardiac Ryanodine Receptor Distribution Is Dynamic and Changed by Auxiliary Proteins and Post-Translational ModificationAsghari, P., et al. | January 16, 2020Read the Publication This week we profile a recent publication in eLife from Dr. Parisa…sciencecityJanuary 16, 2020 Read More
Publications of the Week Low Oxygen Enhances Trophoblast Column Growth by Potentiating Differentiation of the Extravillous Lineage and Promoting LOX ActivityTreissman, J., et al. | January 10, 2020The role of low oxygen in early placental development is controversial and inconclusive. The authors…sciencecityJanuary 10, 2020 Read More
Publications of the Week The Long Non-Coding RNA Cancer Susceptibility 15 Is Induced By Isocitrate Dehydrogenase Mutations And Maintains an Immature Phenotype In Adult Acute Myeloid LeukemiaGrasedieck, S., et al. | January 9, 2020We and others recently showed that coordinated expression of long non-coding RNAs (lncRNAs) is essential…sciencecityJanuary 9, 2020 Read More
Publications of the Week Gradient-Independent Wnt Signalling Instructs Asymmetric Neurite Pruning in C. ElegansLu, M., et al. | December 18, 2019When neurons extend their processes, they often make excessive number of neurites at early stages…sciencecityDecember 18, 2019 Read More
Publications of the Week The Onpattro Story and the Clinical Translation of Nanomedicines Containing Nucleic Acid-Based DrugsAkinc, A., et al. | December 17, 2019The regulatory approval of Onpattro, a lipid nanoparticle-based short interfering RNA drug for the treatment…sciencecityDecember 17, 2019 Read More
Publications of the Week Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle RegenerationScott, R.W., et al. | December 16, 2019The authors examined mesenchymal progenitors (MP) in skeletal muscle regeneration, showing that they play several…sciencecityDecember 16, 2019 Read More
Publications of the Week Initiation of Human Mammary Cell Tumorigenesis by Mutant KRAS Requires YAP InactivationLefort, S., et al. | December 13, 2019High YAP activity is associated with poor prognosis human breast cancers, but its role during…sciencecityDecember 13, 2019 Read More
Publications of the Week Epithelial Tumour Suppressor ELF3 Is a Lineage-Specific Amplified Oncogene in Lung AdenocarcinomaEnfield, K.S.S., et al. | December 11, 2019The authors have found that ELF3, a transcription factor, is a new amplified oncogene in…sciencecityDecember 11, 2019 Read More
Publications of the Week Systematic Phenomics Analysis of Autism-Associated Genes Reveals Parallel Networks Underlying Reversible Impairments in HabituationMcDiarmid, T.A., et al. | December 6, 2019The authors used an automated tracking system to quantify 26 measures spanning morphology, locomotion, tactile…sciencecityDecember 6, 2019 Read More