Publications of the Week Macrophages with Reduced Expressions of Classical M1 and M2 Surface Markers in Human Bronchoalveolar Lavage Fluid Exhibit Pro-Inflammatory Gene Signatures Takiguchi, H., et al. | April 22, 2021 The classical M1/M2 polarity of macrophages may not be applicable to inflammatory lung diseases including…pthomsonApril 22, 2021 Read More
Publications of the Week Targeting AXL Kinase Sensitizes Leukemic Stem and Progenitor Cells to Venetoclax Treatment in Acute Myeloid Leukemia Niu, X., et al. | April 20, 2021 The abundance of genetic abnormalities and phenotypic heterogeneities in AML pose significant challenges to developing…pthomsonApril 20, 2021 Read More
Publications of the Week Cause or Effect? The Spatial Organization of Pathogens and the Gut Microbiota in Disease Nguyen, J., et al. | April 19, 2021 The human gut hosts a dense and diverse microbial community, spatially organized by multiple scales…pthomsonApril 19, 2021 Read More
Publications of the Week The Role of Phosphorylation in Atrial Fibrillation: A Focus on Mass Spectrometry Approaches Safabakhsh, S., et al. | April 14, 2021 Atrial fibrillation is the most common arrhythmia worldwide. It is associated with a doubling in…Sina SafabakhshApril 14, 2021 Read More
Publications of the Week Effect of Small Molecule eRF3 Degraders on Premature Termination Codon Readthrough Baradaran-Heravi, A., et al. | April 13, 2021 Premature termination codon (PTC) readthrough is considered a potential treatment for genetic diseases caused by…pthomsonApril 13, 2021 Read More
Publications of the Week From Infection Niche to Therapeutic Target: The Intracellular Lifestyle of Mycobacterium Tuberculosis Rankine-Wilson, L. I., et al. | April 12, 2021 Mycobacterium tuberculosis (Mtb) is an obligate human pathogen killing millions of people annually. Treatment for tuberculosis…pthomsonApril 12, 2021 Read More
Publications of the Week Resistance to BET Inhibitors in Lung Adenocarcinoma Is Mediated by Casein Kinase Phosphorylation of BRD4 Calder, J. et al. | April 8, 2021 Targeting the epigenome to modulate gene expression programs driving cancer development has emerged as an…pthomsonApril 8, 2021 Read More
Publications of the Week Regulated Cell Death Pathways in Doxorubicin-Induced Cardiotoxicity Christidi, E., and Brunham, L. R. | April 7, 2021 Doxorubicin is a chemotherapeutic drug used for the treatment of various malignancies; however, patients can…pthomsonApril 7, 2021 Read More
Publications of the Week Microchip RT-PCR Detection of Nasopharyngeal SARS-CoV-2 Samples Cojocaruo, R., et al. | April 5, 2021 Fast, accurate and reliable diagnostic tests are critical for controlling the spread of the 2019…pthomsonApril 5, 2021 Read More
Publications of the Week Androgen Receptor (AR) Antagonism Triggers Acute Succinate‐Mediated Adaptive Responses to Reactivate AR Signaling Saxena, N., et al. | March 30, 2021 Androgen receptor (AR) is a major driver of prostate cancer and AR pathway inhibition (ARPI)…pthomsonMarch 30, 2021 Read More