Publications of the Week PODO447: A Novel Antibody to a Tumor-Restricted Epitope on the Cancer Antigen Podocalyxin Hernaez, D.C., et al. | December 2, 2020 The success of new targeted cancer therapies has been dependent on the identification of tumor-specific…eabramovichDecember 2, 2020 Read More
Publications of the Week Single-Cell Analysis of Autophagy Activity in Normal and De Novo Transformed Human Mammary Cells Lefort, S., et al. | November 30, 2020 Assessment of autophagy activity has historically been limited to investigations of fixed tissue or bulk…eabramovichNovember 30, 2020 Read More
Publications of the Week Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis Trinder, M., et al. | November 26, 2020 Previous research from the authors identified that people with a gain-of-function DNA variant in a…eabramovichNovember 26, 2020 Read More
Publications of the Week Beyond Kinases: Targeting Replication Stress Proteins in Cancer Therapy Baillie, K.E., & Stirling, P.C. | November 25, 2020 DNA replication stress describes a state of impaired replication fork progress that triggers a cellular…eabramovichNovember 25, 2020 Read More
Publications of the Week Communal Living: Glycan Utilization by the Human Gut Microbiota Briggs, J.A., et al. | November 23, 2020 Our lower gastrointestinal tract plays host to a vast consortium of microbes, known as the…eabramovichNovember 23, 2020 Read More
Publications of the Week Integrated Expression of Circulating miR375 and miR371 to Identify Teratoma and Active Germ Cell Malignancy Components in Malignant Germ Cell Tumors Nappi, L., et al. | November 20, 2020 Active germ cell malignancies express high levels of specific circulating micro-RNAs (miRNAs), including miR-371a-3p (miR371),…eabramovichNovember 20, 2020 Read More
Publications of the Week Regenerative Intestinal Stem Cells Induced by Acute and Chronic Injury: The Saving Grace of the Epithelium? Rees, W.D., et al. | November 18, 2020 The intestinal epithelium is replenished every 3–4 days through an orderly process that maintains important…eabramovichNovember 18, 2020 Read More
Publications of the Week Coxsackievirus Infection Induces a Non-Canonical Autophagy Independent of the ULK and PI3K Complexes Mohamud, Y., et al. | November 16, 2020 Using established culture models and CRISPR-Cas9 based gene editing, the authors uncover the surprising molecular…eabramovichNovember 16, 2020 Read More
Publications of the Week Abortive γδTCR Rearrangements Suggest ILC2s Are Derived from T-Cell Precursors Shin, S.S., et al. | November 12, 2020 Innate lymphoid cells (ILCs) are a recently identified subset of leukocytes that play a central…eabramovichNovember 12, 2020 Read More
Publications of the Week Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-Parenchymal Cell Lineages Lotto, J., et al. | November 10, 2020 The authors used single-cell transcriptomics to assess the developmental origins of the three main cell…eabramovichNovember 10, 2020 Read More