Publications of the Week Modulation of Innate Immunity by Amyloidogenic PeptidesWestwell-Roper, C. and Verchere C.B. | July 31, 2019Amyloidogenic peptides of both bacterial and mammalian origin transition through multiple aggregation states with distinct…sciencecityJuly 31, 2019 Read More
Publications of the Week Gene Expression Profiles Complement the Analysis of Genomic Modifiers of the Clinical Onset of Huntington DiseaseWright, G.E.B, et al. | July 29, 2019In an attempt to identify genomic modifiers that contribute towards the age of onset of…sciencecityJuly 29, 2019 Read More
Publications of the Week Cryo-EM Structures Reveal Coordinated Domain Motions that Govern DNA Cleavage by Cas9Zhu, X., et al. | July 25, 2019The RNA-guided Cas9 endonuclease from Streptococcus pyogenes is a single-turnover enzyme that displays a stable product state…sciencecityJuly 25, 2019 Read More
Publications of the Week Transcriptional Regulation of Normal Human Mammary Cell Heterogeneity and Its Perturbation in Breast CancerPellacani, D., et al. | July 23, 2019The mammary gland in adult women consists of biologically distinct cell types that differ in…sciencecityJuly 23, 2019 Read More
Publications of the Week New Insights into the Intrinsic and Extrinsic Factors that Shape the Human Skin MicrobiomeDimitriu, P.A., et al. | July 19, 2019Many studies have shown that body site and inter-personal differences shape the composition of the…sciencecityJuly 19, 2019 Read More
Publications of the Week Coding and Non-Coding Drivers of Mantle Cell Lymphoma Identified through Exome and Genome SequencingPararajalingam, P., et al. | July 18, 2019Mantle cell lymphoma (MCL) is an uncommon B-cell non-Hodgkin lymphoma (NHL) that is incurable with…sciencecityJuly 18, 2019 Read More
Publications of the Week Synthetic Modeling Reveals HOXB Genes are Critical for the Initiation and Maintenance of Human LeukemiaKusakabe, M., et al. | July 12, 2019In this manuscript, the authors describe a completely synthetic, efficient, and highly reproducible means for…sciencecityJuly 12, 2019 Read More
Publications of the Week A Positive Feedback Loop between Myc and Aerobic Glycolysis Sustains Tumour Growth in a Drosophila Tumour ModelWong, K.K.L., et al. | July 8, 2019Cancer cells usually exhibit aberrant cell signaling and metabolic reprogramming. However, mechanisms of crosstalk between…sciencecityJuly 8, 2019 Read More
Publications of the Week Neuroprotective Effect of CuATSM on Neurotoxin-Induced Motor Neuron Loss in an ALS Mouse ModelKuo, M.T.H., et al. | July 5, 2019CuATSM, a copper homeostasis regulating compound, has been used as a PET-imaging agent for hypoxic…sciencecityJuly 5, 2019 Read More
Publications of the Week Specific Loss of Adipocyte CD248 Improves Metabolic Health via Reduced White Adipose Tissue Hypoxia, Fibrosis and InflammationPetrus, P., et al. | July 3, 2019Read the Publication This week we profile a recent publication in EBioMedicine from the laboratory…sciencecityJuly 3, 2019 Read More