Publications of the Week Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide SignallingCoulombe, P., et al. | May 21, 2019Lung immaturity is a major cause of respiratory distress and mortality in premature newborns. In…sciencecityMay 21, 2019 Read More
Publications of the Week Upregulation of Scavenger Receptor B1 Is Required for Steroidogenic and Non-Steroidogenic Cholesterol Metabolism in Prostate CancerGordon, J., et al. | May 20, 2019Aberrant cholesterol metabolism is increasingly appreciated to be essential for prostate cancer (PCa) initiation and…sciencecityMay 20, 2019 Read More
Publications of the Week Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA RepressorCaveney, N., et al. | May 15, 2019Bacteria identify and respond to DNA damage using the SOS response. LexA, a central repressor…sciencecityMay 15, 2019 Read More
Publications of the Week The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in a Phosphorylation-Dependent MannerHaji-Ghassemi, O., et al. | May 13, 2019The ryanodine receptor is a channel is of key importance in heart muscle contraction and…sciencecityMay 13, 2019 Read More
Publications of the Week Inhibition of GLI2 with Antisense-Oligonucleotides: A Potential Therapy for the Treatment of Bladder CancerRaven, P.A., et al. | May 10, 2019As a surgeon scientist, Dr. Alan So’s interest in research is to meld both bench…sciencecityMay 10, 2019 Read More
Publications of the Week Cancer Stemness, Intratumoral Heterogeneity, and Immune Response Across CancersMiranda, A., et al. | May 8, 2019Regulatory programs that control the function of stem cells are active in cancer and confer…sciencecityMay 8, 2019 Read More
Publications of the Week Structural Insight into YcbB-Mediated Beta-Lactam Resistance in Escherichia ColiCaveney, N.A., et al. | May 6, 2019In Escherichia coli, the peptidoglycan crosslinking reaction to form the cell wall is primarily carried…sciencecityMay 6, 2019 Read More
Publications of the Week Ibrutinib Displays Atrial-Specific Toxicity in Human Stem Cell-Derived CardiomyocytesShafaattalab, S., et al. | May 3, 2019Ibrutinib (IB) is an oral Bruton's tyrosine kinase (BTK) inhibitor that has demonstrated benefit in…sciencecityMay 3, 2019 Read More
Publications of the Week Fusion-Dependent Formation of Lipid Nanoparticles Containing Macromolecular PayloadsKulkarni, J., et al. | April 29, 2019Previous work from this group has suggested that the structure of lipid nanoparticles (LNPs) contained…sciencecityApril 29, 2019 Read More
Publications of the Week Particle Depletion Does Not Remediate Acute Effects of Traffic-Related Air Pollution and Allergen: A Randomized, Double-Blinded Crossover StudyWooding, D.J., et al. | April 25, 2019Rationale: Diesel exhaust (DE), an established model of traffic-related air pollution, contributes significantly to the…sciencecityApril 25, 2019 Read More