Publications of the Week Fixation Effects on Variant Calling in a Clinical Resequencing PanelParker, J.D.K., et al. | June 27, 2019Formalin fixation is the standard method for the preservation of tissue for diagnostic purposes, including…sciencecityJune 27, 2019 Read More
Publications of the Week Proteomic Profiling to Identify Blood Biomarkers Predictive of Response to Azithromycin in Children and Adolescents with Cystic FibrosisDong, K., et al. | June 25, 2019Abstract Background Azithromycin reduces pulmonary exacerbation (PEx) risk in cystic fibrosis (CF) but not all…sciencecityJune 25, 2019 Read More
Publications of the Week Polycomb Contraction Differentially Regulates Terminal Human Hematopoietic Differentiation ProgramsLorzadeh, A., et al. | June 20, 2019Mature blood cells derive from primitive cells through a complex and poorly understood process that…sciencecityJune 20, 2019 Read More
Publications of the Week Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated FilopodiaBernier, L.P., et al. | June 17, 2019Microglia are highly ramified cells that constantly extend and retract processes to probe their environment…sciencecityJune 17, 2019 Read More
Publications of the Week An Enzymatic Pathway in the Human Gut Microbiome that Converts A to Universal O Type BloodRahfeld, P., et al | June 13, 2019The Withers lab has been interested in using the technique of metagenomics to discover new…sciencecityJune 13, 2019 Read More
Publications of the Week Exome Sequencing in Multiple Sclerosis Families Identifies 12 Candidate Genes and Nominates Biological Pathways for the Genesis of DiseaseVilariño-Güell, C., et al. | June 10, 2019Most treatments for multiple sclerosis (MS) target the adaptive immune and may ameliorate the patients’…sciencecityJune 10, 2019 Read More
Publications of the Week Length of Uninterrupted CAG, Independent of Polyglutamine Size, Results in Increased Somatic Instability, Hastening Onset of Huntington DiseaseWright, G.E.B., et al. | June 7, 2019This study focuses on the area surrounding a pathogenic polyglutamine repeat in patients with Huntington…sciencecityJune 7, 2019 Read More
Publications of the Week Stress-Induced Tunneling Nanotubes Support Treatment Adaptation in Prostate CancerKretschmer, A., et al. | June 4, 2019Tunneling nanotubes (TNTs) are actin-based membranous structures bridging distant cells for intercellular communication. We define…sciencecityJune 4, 2019 Read More
Publications of the Week Characterization of Transcriptomic Signature of Primary Prostate Cancer Analogous to Prostatic Small Cell Neuroendocrine CarcinomaAlshalalfa, M., et al. | May 31, 2019Prostatic small cell neuroendocrine carcinoma (SC/NE) is well studied in metastatic CRPC, however, it is…sciencecityMay 31, 2019 Read More
Publications of the Week ApoA-I Deficiency Increases Cortical Amyloid Deposition, Cerebral Amyloid Angiopathy, Cortical and Hippocampal Astrogliosis, and Amyloid-Associated Astrocyte Reactivity in APP/PS1 MiceButton, E.B., et al. | May 27, 2019This publication shows that mice with low levels of high-density lipoproteins (HDL) (commonly known as…sciencecityMay 27, 2019 Read More