Publications of the Week Beyond Kinases: Targeting Replication Stress Proteins in Cancer Therapy Baillie, K.E., & Stirling, P.C. | November 25, 2020 DNA replication stress describes a state of impaired replication fork progress that triggers a cellular…eabramovichNovember 25, 2020 Read More
Publications of the Week Communal Living: Glycan Utilization by the Human Gut Microbiota Briggs, J.A., et al. | November 23, 2020 Our lower gastrointestinal tract plays host to a vast consortium of microbes, known as the…eabramovichNovember 23, 2020 Read More
Publications of the Week Integrated Expression of Circulating miR375 and miR371 to Identify Teratoma and Active Germ Cell Malignancy Components in Malignant Germ Cell Tumors Nappi, L., et al. | November 20, 2020 Active germ cell malignancies express high levels of specific circulating micro-RNAs (miRNAs), including miR-371a-3p (miR371),…eabramovichNovember 20, 2020 Read More
Publications of the Week Regenerative Intestinal Stem Cells Induced by Acute and Chronic Injury: The Saving Grace of the Epithelium? Rees, W.D., et al. | November 18, 2020 The intestinal epithelium is replenished every 3–4 days through an orderly process that maintains important…eabramovichNovember 18, 2020 Read More
Publications of the Week Coxsackievirus Infection Induces a Non-Canonical Autophagy Independent of the ULK and PI3K Complexes Mohamud, Y., et al. | November 16, 2020 Using established culture models and CRISPR-Cas9 based gene editing, the authors uncover the surprising molecular…eabramovichNovember 16, 2020 Read More
Publications of the Week Abortive γδTCR Rearrangements Suggest ILC2s Are Derived from T-Cell Precursors Shin, S.S., et al. | November 12, 2020 Innate lymphoid cells (ILCs) are a recently identified subset of leukocytes that play a central…eabramovichNovember 12, 2020 Read More
Publications of the Week Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-Parenchymal Cell Lineages Lotto, J., et al. | November 10, 2020 The authors used single-cell transcriptomics to assess the developmental origins of the three main cell…eabramovichNovember 10, 2020 Read More
Publications of the Week TRIM25 Promotes Capicua Degradation Independently of ERK in the Absence of ATXN1L Wong, D., et al. | November 6, 2020 The authors broaden the understanding of the post-translational regulation of Capicua (CIC), which has now…eabramovichNovember 6, 2020 Read More
Publications of the Week Sexual Dimorphism: Ecdysone Modulates Sex Differences in the Gut Millington, J.W., & Rideout, E.J. | November 3, 2020 Sex differences in the Drosophila gut were discovered only recently. Recent work significantly extends our understanding of…eabramovichNovember 3, 2020 Read More
Publications of the Week SUSA2 Is an F-Box Protein Required for Autoimmunity Mediated by Paired NLRs SOC3-CHS1 and SOC3-TN2 Liang, W., et al. | October 30, 2020 Both higher plants and mammals rely on nucleotide-binding leucine-rich repeat (NLR) immune receptors to detect…eabramovichOctober 30, 2020 Read More