Publications of the Week The Epigenomics of Sarcoma Nacev, B.A., et al. | August 17, 2020 Epigenetic regulation is critical to physiological control of development, cell fate, cell proliferation, genomic integrity…eabramovichAugust 17, 2020 Read More
Publications of the Week β1 Integrin, ILK and mTOR Regulate Collagen Synthesis in Mechanically Loaded Tendon Cells Mousavizadeh, R., et al. | August 14, 2020 The authors discovered that tendon cells respond to mechanical stimuli via integrins. Integrin β1 and…eabramovichAugust 14, 2020 Read More
Publications of the Week The Stringent Stress Response Controls Proteases and Global Regulators under Optimal Growth Conditions in Pseudomonas aeruginosa Pletzer, D., et al. | August 13, 2020 The bacterial stringent stress response, mediated by the signaling molecule guanosine tetraphosphate, ppGpp, has recently…eabramovichAugust 13, 2020 Read More
Publications of the Week Sustained Depletion of FXIII-A by Inducing Acquired FXIII-B Deficiency Strilchuk, A.W., et al. | August 7, 2020 This work, describing siRNA targeting FXIII-B (siFXIIIB), is the first pharmacologic approach for long-acting, reversible,…eabramovichAugust 7, 2020 Read More
Publications of the Week Frequency of the Loss of CAA Interruption in the HTT CAG Tract and Implications for Huntington Disease in the Reduced Penetrance Range Black, H.F., et al. | August 6, 2020 In some Huntington disease (HD) patients, the “loss of interruption” (LOI) variant eliminates an interrupting…eabramovichAugust 6, 2020 Read More
Publications of the Week Single Cell Transcriptomes of Normal Endometrial Derived Organoids Uncover Novel Cell Type Markers and Cryptic Differentiation of Primary Tumours Cochrane, D.R., et al. | July 30, 2020 Endometrial carcinoma, the most common gynaecological cancer, develops from endometrial epithelium which is composed of…eabramovichJuly 30, 2020 Read More
Publications of the Week The Pathognomonic FOXL2 C134W Mutation Alters DNA Binding Specificity Carles, A., et al. | July 28, 2020 The somatic missense point mutation c.402C>G (p.C134W) in the FOXL2 transcription factor is pathognomonic for…eabramovichJuly 28, 2020 Read More
Publications of the Week Integrins Modulate Extracellular Matrix Organization to Control Cell Signaling during Hematopoiesis Khadilkar, R.J., et al. | July 23, 2020 The authors show that integrins play a key role during fly hematopoiesis in regulating cell…eabramovichJuly 23, 2020 Read More
Publications of the Week LIN28B Promotes the Development of Neuroendocrine Prostate Cancer Lovnicki, J.M., et al. | July 20, 2020 Compelling evidence has shown that LIN28b plays an important role in regulating the lineage switch…eabramovichJuly 20, 2020 Read More
Publications of the Week Genetic and Evolutionary Patterns of Treatment Resistance in Relapsed B-Cell Lymphoma Rushton, C.K., et al. | July 17, 2020 This study not only uncovers mechanisms of diffuse large B cell lymphoma (DLBCL) treatment resistance,…eabramovichJuly 17, 2020 Read More