Publications of the Week EFHC1, Implicated in Juvenile Myoclonic Epilepsy, Functions at the Cilium and Synapse to Modulate Dopamine SignallingLoucks, C.M., et al. | March 19, 2019The authors identified roles for a protein called EFHC1 at both the cilium and the…sciencecityMarch 19, 2019 Read More
Publications of the Week A Topological View of Human CD34+ Cell State Trajectories from Integrated Single-Cell Output and Proteomic DataKnapp, D.J.H.F., et al. | March 15, 2019The authors created highly detailed functional and protein maps of the entire blood stem and…sciencecityMarch 15, 2019 Read More
Publications of the Week A Topological View of Human CD34+ Cell State Trajectories from Integrated Single-Cell Output and Proteomic DataKnapp, D.J.H.F., et al. | March 15, 2019The authors created highly detailed functional and protein maps of the entire blood stem and…mjoyMarch 15, 2019 Read More
Publications of the Week Huntingtin Lowering Strategies for Disease Modification in Huntington’s DiseaseTabrizi, S.J., et al. | March 11, 2019Huntington’s disease is caused by an abnormally expanded CAG repeat expansion in the HTT gene, which confers a…sciencecityMarch 11, 2019 Read More
Publications of the Week Metagenomic and Metatranscriptomic Analysis of Human Prostate Microbiota from Patients with Prostate CancerFeng, Y., et al. | March 7, 2019Prostate cancer (PCa) is the most common malignant neoplasm among men in many countries. Since…sciencecityMarch 7, 2019 Read More
Publications of the Week Association of a Placental Interleukin-6 Genetic Variant (rs1800796) with DNA Methylation, Gene Expression and Risk of Acute ChorioamnionitisKonwar, C., et al. | March 5, 2019Background Acute chorioamnionitis (aCA), inflammation of the placenta and fetal membranes, is a frequently reported…sciencecityMarch 5, 2019 Read More
Publications of the Week Podocalyxin Is Required for Maintaining Blood–Brain Barrier Function During Acute InflammationCait, J., et al. | March 1, 2019The blood-brain barrier (BBB) separates the brain from circulating blood and it is essential for…sciencecityMarch 1, 2019 Read More
Publications of the Week The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic ShockArora, H., et al. | February 25, 2019The authors conducted a gene expression screen to identify genes controlling innate and adaptive immunity,…sciencecityFebruary 25, 2019 Read More
Publications of the Week Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune RecognitionEnnishi, D., et al. | February 21, 2019In their most current integrative genomics studies the authors discovered the genetic and molecular features…sciencecityFebruary 21, 2019 Read More
Publications of the Week A High-Throughput Protocol for Isolating Cell-Free Circulating Tumour DNA from Peripheral BloodPandoh, P.K., et al. | February 19, 2019Standard isolation of ctDNA involves the separation of plasma by centrifugation followed by column or…sciencecityFebruary 19, 2019 Read More