Publications of the Week Sunflower Pan-Genome Analysis Shows That Hybridization Altered Gene Content and Disease ResistanceHubner, S., et al. | January 18, 2019Domesticated plants and animals often display dramatic responses to selection, but the origins of the…sciencecityJanuary 18, 2019 Read More
Publications of the Week Differential Regulation of TNL-Mediated Immune Signaling by Redundant Helper CNLsWu, Z., et al. | January 15, 2019Higher plants utilize nucleotide-binding leucine-rich repeat domain proteins (NLRs) as intracellular immune receptors to recognize…sciencecityJanuary 15, 2019 Read More
Publications of the Week Integration of DNA Methylation Patterns and Genetic Variation in Human Pediatric Tissues Help Inform EWAS Design and InterpretationIslam, S.A., et al. | January 7, 2019The widespread use of accessible peripheral tissues for epigenetic analyses has prompted increasing interest in…sciencecityJanuary 7, 2019 Read More
Publications of the Week Bottoms Up: The Role of Gut Microbiota in Brain HealthRadisavljevic, N., et al. | January 3, 2019The gut microbiota affects many aspects of human health, and research, especially over the past…sciencecityJanuary 3, 2019 Read More
Publications of the Week Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic ProgenitorsKrentz, N.A.J., et al. | January 2, 2019Human embryonic stem cells (hESCs) are a potential unlimited source of insulin-producing β cells for…sciencecityJanuary 2, 2019 Read More
Publications of the Week Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell LymphomaEnnishi, D., et al. | December 14, 2018Purpose High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-DH/TH) has a poor outcome after standard chemoimmunotherapy. We sought…sciencecityDecember 14, 2018 Read More
Publications of the Week IL-13 Signaling through IL-13 Receptor α2 Mediates Airway Epithelial Wound RepairYang, S. J., et al. | December 13, 2018The results presented in this manuscript demonstrate the role for the IL13 receptor Rα2 in…sciencecityDecember 13, 2018 Read More
Publications of the Week IVIg and LPS Co-Stimulation Induces IL-10 Production by Human Monocytes, which Is Compromised by an FcγRIIA Disease-Associated Gene VariantKozicky, L.K., et al. | December 6, 2018Intravenous Immunoglobulin (IVIg) is used to treat autoimmune or inflammatory diseases, but its mechanism of…sciencecityDecember 6, 2018 Read More
Publications of the Week Cellular Metabolism Constrains Innate Immune Responses in Early Human OntogenyKan, B., et al. | December 3, 2018We have known for many years that these first-line responses, which are crucial to fight…sciencecityDecember 3, 2018 Read More
Publications of the Week Identification of a Novel Caspase Cleavage Site in Huntingtin that Regulates Mutant Huntingtin ClearanceMartin, D.D.O., et al. | November 30, 2018A caspase-1 inhibitor was shown to decrease not only caspase-1-mediated cleavage of HTT at 572,…sciencecityNovember 30, 2018 Read More