Publications of the Week Antisense Oligonucleotides for Neurodegeneration Leavitt, B.R., & Tabrizi, S.J. | April 10, 2020 Antisense oligonucleotides (ASOs) have the potential to reduce, restore, or modify RNA and protein expression.…sciencecityApril 10, 2020 Read More
Publications of the Week Distinct Inactivated Bacterial-Based Immune Modulators Vary in their Therapeutic Efficacies for Treating Disease Based on the Organ Site of Pathology Kalyan, S., et al. | April 8, 2020 Recent developments in understanding how the functional phenotype of the innate immune system is programmed…sciencecityApril 8, 2020 Read More
Publications of the Week Cerebrovascular Amyloid Angiopathy in Bioengineered Vessels Is Reduced by High-Density Lipoprotein Particles Enriched in Apolipoprotein E Robert, J., et al. | April 3, 2020 Several lines of evidence suggest that high-density lipoprotein (HDL) reduces Alzheimer’s disease (AD) risk by…sciencecityApril 3, 2020 Read More
Publications of the Week Germline CRISPR/Cas9-Mediated Gene Editing Prevents Vision Loss in a Novel Mouse Model of Aniridia Mohanna, S.Z.M., et al. | March 30, 2020 Aniridia is a rare genetic disease that reduces vision from birth and progresses to blindness…sciencecityMarch 30, 2020 Read More
Publications of the Week Premature Termination Codon Readthrough Upregulates Progranulin Expression and Improves Lysosomal Function in Preclinical Models of GRN Deficiency Molecular Neurodegeneration | March 27, 2020 Frontotemporal lobar degeneration (FTLD) is a devastating and progressive disorder, and a common cause of…sciencecityMarch 27, 2020 Read More
Publications of the Week A Model of Differential Mammary Growth Initiation by Stat3 and Asymmetric Integrin-α6 Inheritance Morris, E.J., et al. | March 26, 2020 The authors describe a very interesting mechanism for the regulation of symmetric versus asymmetric cellular…sciencecityMarch 26, 2020 Read More
Publications of the Week Cross-Species Complementation of Nonessential Yeast Genes Establishes Platforms for Testing Inhibitors of Human Proteins Hamza, A., et al. | March 20, 2020 Cross-species complementation can be used to generate humanized yeast, which is a valuable resource with…sciencecityMarch 20, 2020 Read More
Publications of the Week Identification of Alzheimer’s Disease–Associated Rare Coding Variants in the ECE2 Gene Liao, X., et al. | March 18, 2020 Accumulation of amyloid β protein (Aβ) due to increased generation and/or impaired degradation plays an…sciencecityMarch 18, 2020 Read More
Publications of the Week Coding and Non-Coding Drivers of Mantle Cell Lymphoma Identified through Exome and Genome Sequencing Pararajalingam, P., et al. | March 13, 2020 Mantle cell lymphoma (MCL) is an uncommon B-cell non-Hodgkin lymphoma (NHL) that is incurable with…sciencecityMarch 13, 2020 Read More
Publications of the Week Distinct Features of Stress Granule Proteins Predict Localization in Membraneless Organelle Kuechler, E.R., et al. | March 12, 2020 Recently generated proteomic data provides unprecedented insight into stress granule composition and stands as fruitful…sciencecityMarch 12, 2020 Read More