Publications of the Week Transcriptional Regulation of Normal Human Mammary Cell Heterogeneity and Its Perturbation in Breast CancerPellacani, D., et al. | July 23, 2019The mammary gland in adult women consists of biologically distinct cell types that differ in…sciencecityJuly 23, 2019 Read More
Publications of the Week New Insights into the Intrinsic and Extrinsic Factors that Shape the Human Skin MicrobiomeDimitriu, P.A., et al. | July 19, 2019Many studies have shown that body site and inter-personal differences shape the composition of the…sciencecityJuly 19, 2019 Read More
Publications of the Week Coding and Non-Coding Drivers of Mantle Cell Lymphoma Identified through Exome and Genome SequencingPararajalingam, P., et al. | July 18, 2019Mantle cell lymphoma (MCL) is an uncommon B-cell non-Hodgkin lymphoma (NHL) that is incurable with…sciencecityJuly 18, 2019 Read More
Publications of the Week Synthetic Modeling Reveals HOXB Genes are Critical for the Initiation and Maintenance of Human LeukemiaKusakabe, M., et al. | July 12, 2019In this manuscript, the authors describe a completely synthetic, efficient, and highly reproducible means for…sciencecityJuly 12, 2019 Read More
Publications of the Week A Positive Feedback Loop between Myc and Aerobic Glycolysis Sustains Tumour Growth in a Drosophila Tumour ModelWong, K.K.L., et al. | July 8, 2019Cancer cells usually exhibit aberrant cell signaling and metabolic reprogramming. However, mechanisms of crosstalk between…sciencecityJuly 8, 2019 Read More
Publications of the Week Neuroprotective Effect of CuATSM on Neurotoxin-Induced Motor Neuron Loss in an ALS Mouse ModelKuo, M.T.H., et al. | July 5, 2019CuATSM, a copper homeostasis regulating compound, has been used as a PET-imaging agent for hypoxic…sciencecityJuly 5, 2019 Read More
Publications of the Week Specific Loss of Adipocyte CD248 Improves Metabolic Health via Reduced White Adipose Tissue Hypoxia, Fibrosis and InflammationPetrus, P., et al. | July 3, 2019Read the Publication This week we profile a recent publication in EBioMedicine from the laboratory…sciencecityJuly 3, 2019 Read More
Publications of the Week Therapeutic Implication of Genomic Landscape of Adult Metastatic SarcomaFeng, X., et al. | June 28, 2019PURPOSE This study investigated therapeutic potential of integrated genome and transcriptome profiling of metastatic sarcoma,…sciencecityJune 28, 2019 Read More
Publications of the Week Fixation Effects on Variant Calling in a Clinical Resequencing PanelParker, J.D.K., et al. | June 27, 2019Formalin fixation is the standard method for the preservation of tissue for diagnostic purposes, including…sciencecityJune 27, 2019 Read More
Publications of the Week Proteomic Profiling to Identify Blood Biomarkers Predictive of Response to Azithromycin in Children and Adolescents with Cystic FibrosisDong, K., et al. | June 25, 2019Abstract Background Azithromycin reduces pulmonary exacerbation (PEx) risk in cystic fibrosis (CF) but not all…sciencecityJune 25, 2019 Read More