Publications of the Week Suppressing Interferon Gamma Stimulates Microglial Responses and Repair of Microbleeds in the Diabetic BrainTaylor, S., et al. | September 26, 2018Microcirculatory damage is a common complication for those with vascular risk factors such as diabetes.…sciencecitySeptember 26, 2018 Read More
Publications of the Week Calcium Channelopathies: Structural Insights into Disorders of the Muscle Excitation-Contraction ComplexPancaroglu, R. and Van Petegem, F. | September 24, 2018Ion channels are membrane proteins responsible for the passage of ions down their electrochemical gradients…sciencecitySeptember 24, 2018 Read More
Publications of the Week Rivaroxaban and Apixaban Induce Clotting Factor Xa Fibrinolytic ActivityCarter, R.L.R., et al. | September 21, 2018In previous years, the Canadian Blood Services’ Pryzdial lab at the UBC Centre for Blood…sciencecitySeptember 21, 2018 Read More
Publications of the Week Transcriptomic Evidence for Alterations in Astrocytes and Parvalbumin Interneurons in Subjects with Bipolar Disorder and SchizophreniaToker, L., et al. | September 17, 2018High-throughput expression analyses of postmortem brain tissue have been widely used to study bipolar disorder…sciencecitySeptember 17, 2018 Read More
Publications of the Week Selectively Targeting the Dimerization Interface of Human Androgen Receptor with Small-Molecules to Treat Castration-Resistant Prostate CancerDalal, K., et al. | September 14, 2018The Rennie and Cherkasov labs have a long history of developing therapeutics to target the…sciencecitySeptember 14, 2018 Read More
Publications of the Week CALCOCO2/NDP52 and SQSTM1/p62 Differentially Regulate Coxsackievirus B3 PropagationMohamud, Y., et al. | September 11, 2018Cell autonomous immunity is the ability of individual cells to initiate a first line of…sciencecitySeptember 11, 2018 Read More
Publications of the Week Mechanical Anisotropy in GNNQQNY Amyloid CrystalsNassar, R., et al. | September 6, 2018Mapping the nanomechanical properties of amyloids can provide valuable insights into structure and assembly mechanisms…sciencecitySeptember 6, 2018 Read More
Publications of the Week LTR Retrotransposons Transcribed in Oocytes Drive Species-Specific and Heritable Changes in DNA MethylationBrind'Amour, J., et al. | September 4, 2018In this study, we characterized the role of a specific class of repetitive elements in…sciencecitySeptember 4, 2018 Read More
Publications of the Week Locomotor Recovery Following Contusive Spinal Cord Injury Does Not Require Oligodendrocyte RemyelinationDuncan, G.J., et al. | August 31, 2018Remyelination occurs after spinal cord injury (SCI) but its functional relevance is unclear. We assessed…sciencecityAugust 31, 2018 Read More
Publications of the Week Revealing the Mechanism for Covalent Inhibition of Glycoside Hydrolases by Carbasugars at an Atomic LevelRen, W., et al. | August 29, 2018Mechanism-based glycoside hydrolase inhibitors are carbohydrate analogs that mimic the natural substrate's structure. Their covalent…sciencecityAugust 29, 2018 Read More