Publications of the Week The Pathognomonic FOXL2 C134W Mutation Alters DNA Binding Specificity Carles, A., et al. | July 28, 2020 The somatic missense point mutation c.402C>G (p.C134W) in the FOXL2 transcription factor is pathognomonic for…eabramovichJuly 28, 2020 Read More
Publications of the Week Integrins Modulate Extracellular Matrix Organization to Control Cell Signaling during Hematopoiesis Khadilkar, R.J., et al. | July 23, 2020 The authors show that integrins play a key role during fly hematopoiesis in regulating cell…eabramovichJuly 23, 2020 Read More
Publications of the Week LIN28B Promotes the Development of Neuroendocrine Prostate Cancer Lovnicki, J.M., et al. | July 20, 2020 Compelling evidence has shown that LIN28b plays an important role in regulating the lineage switch…eabramovichJuly 20, 2020 Read More
Publications of the Week Genetic and Evolutionary Patterns of Treatment Resistance in Relapsed B-Cell Lymphoma Rushton, C.K., et al. | July 17, 2020 This study not only uncovers mechanisms of diffuse large B cell lymphoma (DLBCL) treatment resistance,…eabramovichJuly 17, 2020 Read More
Publications of the Week Bax and Bak Jointly Control Survival and Dampen the Early Unfolded Protein Response in Pancreatic β-Cells Under Glucolipotoxic Stress White, S.A., et al. | July 16, 2020 This work sheds new light on the molecular machinery that controls β-cell survival. The authors…eabramovichJuly 16, 2020 Read More
Publications of the Week Improved Structural Variant Interpretation for Hereditary Cancer Susceptibility Using Long-Read Sequencing Thibodeau, M.L., et al. | July 13, 2020 The researchers employed the Oxford Nanopore PromethION long-read sequencer to re-sequence and analyze the genomes…eabramovichJuly 13, 2020 Read More
Publications of the Week AAV8 Ins1-Cre Can Produce Efficient β-Cell Recombination but Requires Consideration of Off-Target Effects Ramzy, A., et al. | July 10, 2020 The Cre-LoxP system, which uses a tool borrowed from viruses, is the most prevalent technology…eabramovichJuly 10, 2020 Read More
Publications of the Week MYC-Induced Human Acute Myeloid Leukemia Requires a Continuing IL3/GM-CSF Co-Stimulus Bulaeva, E., et al. | July 8, 2020 Hematopoietic clones with leukemogenic mutations arise in healthy people as they age, but progression to…eabramovichJuly 8, 2020 Read More
Publications of the Week Suboptimal Biological Sampling as a Probable Cause of False-Negative COVID-19 Diagnostic Test Results Kinloch, N.N., et al. | July 6, 2020 Although nasopharyngeal swabs are routinely ordered for respiratory viruses, it was long speculated that improper…eabramovichJuly 6, 2020 Read More
Publications of the Week Multi-Omic Approach to Identify Phenotypic Modifiers Underlying Cerebral Demyelination in X-Linked Adrenoleukodystrophy Richmond, P.A., et al. | July 2, 2020 X-linked adrenoleukodystrophy (ALD) is a peroxisomal metabolic disorder with a highly complex clinical presentation. ALD…eabramovichJuly 2, 2020 Read More