Publications of the Week Utilizing Organoid and Air-Liquid Interface Models as a Screening Method in the Development of New Host Defense PeptidesChoi, K.Y.G., et al. | May 28, 2020Host defense peptides (HDPs), also known as antimicrobial peptides, are naturally occurring polypeptides (~12–50 residues)…eabramovichMay 28, 2020 Read More
Publications of the Week Deregulated Regulators: Disease-Causing cis Variants in Transcription Factor Genesvan der Lee, R., et al. | May 26, 2020Challenges in the interpretation of whole-genome sequences leave rare disease cases undiagnosed. Cis-regulatory variants are anticipated…eabramovichMay 26, 2020 Read More
Publications of the Week Altered microRNA Expression Links IL6 and TNF-Induced Inflammaging with Myeloid MalignancyGrants, J.M., et al. | May 25, 2020This study reveals how regulation of a microRNA links aging, inflammation and the development of…eabramovichMay 25, 2020 Read More
Publications of the Week Overexpression of the Small RNA PA0805.1 in Pseudomonas aeruginosa Modulates the Expression of a Large Set of Genes and Proteins, Resulting in Altered Motility, Cytotoxicity, and Tobramycin ResistanceColeman, S.R., et al. | May 21, 2020Pseudomonas aeruginosa is a motile species that initiates swarming motility in response to specific environmental cues,…eabramovichMay 21, 2020 Read More
Publications of the Week Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of CancerBabaian, A., et al. | May 19, 2020The authors found that there is a ribosomal RNA hyper-modification called 1-methyl-3-α-amino-α-carboxyl-propyl pseudouridine (macpΨ) that…eabramovichMay 19, 2020 Read More
Publications of the Week Towards Stem Cell Therapies for Skeletal Muscle RepairJudson, R.N., & Rossi, F.M.V. | May 14, 2020Skeletal muscle is an ideal target for cell therapy. The use of its potent stem…eabramovichMay 14, 2020 Read More
Publications of the Week His-Tagged Peptidiscs Enable Affinity Purification of the Membrane Proteome for Downstream Mass Spectrometry AnalysisYoung, J., et al. | May 13, 2020Detergents are not compatible with mass spectrometry, and their removal from biological samples often results…eabramovichMay 13, 2020 Read More
Publications of the Week A Sparse, Spatially Biased Subtype of Mature Granule Cell Dominates Recruitment in Hippocampal-Associated BehaviorsErwin, S.R., et al. | May 11, 2020To try and decipher how precisely granule cells of the dentate gyrus contribute to hippocampal…eabramovichMay 11, 2020 Read More
Publications of the Week ntJoin: Fast and Lightweight Assembly-Guided Scaffolding Using Minimizer GraphsCoombe, L., et al. | May 7, 2020The Bioinformatics Technology Lab at Canada’s Michael Smith Genome Sciences Centre (GSC) at BC Cancer…eabramovichMay 7, 2020 Read More
Publications of the Week Pan-Cancer Analysis of Advanced Patient Tumors Reveals Interactions Between Therapy and Genomic LandscapesPleasance, E., et al. | May 5, 2020This in-depth analysis of the first cohort from BC Cancer’s Personalized OncoGenomics Program provides a…eabramovichMay 5, 2020 Read More