Publications of the Week Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer Robertson, G.A., et al. | November 10, 2017 Bladder cancer is the ninth most common cancer globally, and is the most expensive to…sciencecityNovember 10, 2017 Read More
Publications of the Week LAG-3+ Tumor Infiltrating Lymphocytes in Breast Cancer: Clinical Correlates and Association with PD-1/PD-L1+ Tumors Burugu, S. and Nielsen, T.O., et al. | November 8, 2017 Novel immune checkpoint blockade strategies are being evaluated in clinical trials and include targeting the…sciencecityNovember 8, 2017 Read More
Publications of the Week Investigating Immune Gene Signatures in Peripheral Blood from Subjects with Allergic Rhinitis Undergoing Nasal Allergen Challenge Kim, Y.W. and Tebbutt, S.J., et al. | November 6, 2017 We discovered systemic immune response signatures that were highly correlated to upper airway clinical symptom…sciencecityNovember 6, 2017 Read More
Publications of the Week Participant Selection for Lung Cancer Screening by Risk Modelling: a Single-Arm, Prospective Study Tammemagi, M.C. and Lam, S., et al. | November 2, 2017 Results from retrospective studies indicate that selecting individuals for low-dose CT lung cancer screening on the basis of a highly…sciencecityNovember 2, 2017 Read More
Publications of the Week Engineered In-Vitro Cell Line Mixtures and Robust Evaluation of Computational Methods for Clonal Decomposition and Longitudinal Dynamics in Cancer Farahani, H. and Shah, S., et al. | November 1, 2017 Characterization and quantification of tumour clonal populations over time via longitudinal sampling are essential components…sciencecityNovember 1, 2017 Read More
Publications of the Week RECQ-Like Helicases Sgs1 and BLM Regulate R-Loop-Associated Genome Instability Chang, E.Y. and Stirling, P.C., et al. | October 30, 2017 Sgs1, the orthologue of human Bloom's syndrome helicase BLM, is a yeast DNA helicase functioning…sciencecityOctober 30, 2017 Read More
Publications of the Week Antimicrobial Resistance Gene Acquisition and Depletion Following Fecal Microbiota Transplantation (FMT) for Recurrent Clostridium Difficile Infection Leung, V. and Manges, A.R., et al. | October 26, 2017 Fecal microbiota transplantation (FMT) may be a novel approach to eliminate multidrug-resistant bacteria from the…sciencecityOctober 26, 2017 Read More
Publications of the Week REVIEW: Emerging Targets in Cancer Immunotherapy Burugu, S. and Nielsen, T.O., et al. | October 25, 2017 The first generation of immune checkpoint inhibitors (anti-CTLA-4 and anti-PD-1/PD-L1) targeted natural immune homeostasis pathways,…sciencecityOctober 25, 2017 Read More
Publications of the Week Multi-Target-Directed Phenol-Triazole Ligands as Therapeutic Agents for Alzheimer’s Disease Jones, M.R. and Storr, T., et al. | October 23, 2017 This work was spearheaded by a former graduate student Michael Jones (5th from left) who…sciencecityOctober 23, 2017 Read More
Publications of the Week Self-Biotinylation of DNA G-Quadruplexes via Intrinsic Peroxidase Activity Einarson, O.J. and Sen, D. | October 20, 2017 The striking and ubiquitous in vitro affinity between hemin and DNA/RNA G-quadruplexes raises the intriguing…sciencecityOctober 20, 2017 Read More