Publications of the Week Loss-Of-Function and Gain-Of-Function Mutations in KCNQ5 Cause Intellectual Disability or Epileptic EncephalopathyLehman, A. and Claydon, T., et al. | July 19, 2017KCNQ5 is a highly conserved gene encoding an important channel for neuronal function; it is…sciencecityJuly 19, 2017 Read More
Publications of the Week Clear Cell and Endometrioid Carcinomas: Are Their Differences Attributable to Distinct Cells of Origin?Cochrane, D.R. and Huntsman, D.G., et al. | July 17, 2017Endometrial epithelium is the presumed tissue of origin for both eutopic and endometriosis-derived clear cell…sciencecityJuly 17, 2017 Read More
Publications of the Week Optogenetic Rewiring of Thalamocortical Circuits to Restore Function in the Stroke Injured BrainTennant, K.A. and Brown, C.E., et al. | July 14, 2017Read the Publication This week we profile a recent publication in Nature Communications from Dr.…sciencecityJuly 14, 2017 Read More
Publications of the Week Myelin Regulatory Factor Drives Remyelination in Multiple SclerosisDuncan, G.J. and Tetzlaff, W., et al. | July 12, 2017Remyelination is limited in the majority of multiple sclerosis (MS) lesions despite the presence of…sciencecityJuly 12, 2017 Read More
Publications of the Week REVIEW: Synthetic Lethality and CancerO'Neil, N.J. and Hieter, P., et al. | July 10, 2017A synthetic lethal interaction occurs between two genes when the perturbation of either gene alone…sciencecityJuly 10, 2017 Read More
Publications of the Week BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer’s PathogenesisZhang, S. and Song, W., et al. | July 6, 2017Mutations in amyloid β precursor protein (APP) gene alter APP processing, either causing familial Alzheimer's…sciencecityJuly 6, 2017 Read More
Publications of the Week A Heme-Dependent Enzyme Forms the Nitrogen-Nitrogen Bond in PiperazateDu, Y.L. and Ryan, K.S., et al. | July 5, 2017Molecules containing a nitrogen-nitrogen (N-N) linkage have a variety of structures and biological activities; however,…sciencecityJuly 5, 2017 Read More
Publications of the Week PD-L1 and Intratumoral Immune Response in Breast CancerWang, Z.Q. and Watson, P.H., et al. | July 4, 2017PD-L1 is thought to play an important role in the antitumor immune response. In this…sciencecityJuly 4, 2017 Read More
Publications of the Week Relatively Frequent Switching of Transcription Start Sites during Cerebellar DevelopmentZhang, P. and Goldowitz, D., et al. | June 30, 2017Alternative transcription start site (TSS) usage plays important roles in transcriptional control of mammalian gene…sciencecityJune 30, 2017 Read More
Publications of the Week GATA3 Immunohistochemistry for Distinguishing Sarcomatoid and Desmoplastic Mesothelioma from Sarcomatoid Carcinoma of the LungBerb, K.B. and Churg, A. | June 28, 2017The separation of sarcomatoid and desmoplastic malignant mesotheliomas from sarcomatoid carcinomas of the lung metastatic…sciencecityJune 28, 2017 Read More