Publications of the Week Myelin Regulatory Factor Drives Remyelination in Multiple SclerosisDuncan, G.J. and Tetzlaff, W., et al. | July 12, 2017Remyelination is limited in the majority of multiple sclerosis (MS) lesions despite the presence of…sciencecityJuly 12, 2017 Read More
Publications of the Week REVIEW: Synthetic Lethality and CancerO'Neil, N.J. and Hieter, P., et al. | July 10, 2017A synthetic lethal interaction occurs between two genes when the perturbation of either gene alone…sciencecityJuly 10, 2017 Read More
Publications of the Week BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer’s PathogenesisZhang, S. and Song, W., et al. | July 6, 2017Mutations in amyloid β precursor protein (APP) gene alter APP processing, either causing familial Alzheimer's…sciencecityJuly 6, 2017 Read More
Publications of the Week A Heme-Dependent Enzyme Forms the Nitrogen-Nitrogen Bond in PiperazateDu, Y.L. and Ryan, K.S., et al. | July 5, 2017Molecules containing a nitrogen-nitrogen (N-N) linkage have a variety of structures and biological activities; however,…sciencecityJuly 5, 2017 Read More
Publications of the Week PD-L1 and Intratumoral Immune Response in Breast CancerWang, Z.Q. and Watson, P.H., et al. | July 4, 2017PD-L1 is thought to play an important role in the antitumor immune response. In this…sciencecityJuly 4, 2017 Read More
Publications of the Week Relatively Frequent Switching of Transcription Start Sites during Cerebellar DevelopmentZhang, P. and Goldowitz, D., et al. | June 30, 2017Alternative transcription start site (TSS) usage plays important roles in transcriptional control of mammalian gene…sciencecityJune 30, 2017 Read More
Publications of the Week GATA3 Immunohistochemistry for Distinguishing Sarcomatoid and Desmoplastic Mesothelioma from Sarcomatoid Carcinoma of the LungBerb, K.B. and Churg, A. | June 28, 2017The separation of sarcomatoid and desmoplastic malignant mesotheliomas from sarcomatoid carcinomas of the lung metastatic…sciencecityJune 28, 2017 Read More
Publications of the Week Targeting BCR-ABL+ Stem/Progenitor Cells and BCR-ABL-T315I Mutant Cells by Effective Inhibition of the BCR-ABL-Tyr177-GRB2 ComplexChen, M. and Jiang, X., et al. | June 26, 2017Read the Publication This week we profile a recent publication in Oncotarget from the laboratory…sciencecityJune 26, 2017 Read More
Publications of the Week Reduced Antibody Response to Infant Measles Vaccination: Effects Based on Type and Timing of the First Vaccine Dose Persist after the Second DoseSkowronski, D.M., et al. | June 23, 2017The effect of age at first dose on the immunogenicity of a two-dose pediatric schedule…sciencecityJune 23, 2017 Read More
Publications of the Week MYCN Amplified Neuroblastoma Requires the mRNA Translation Regulator eEF2 Kinase to Adapt to Nutrient DeprivationDelaidelli, A. and Sorensen, P.H., et al. | June 19, 2017Every day, 43 children are diagnosed with cancer in North America. Although there have been…sciencecityJune 19, 2017 Read More