Publications of the Week An Oncofetal Glycosaminoglycan Modification Provides Therapeutic Access to Cisplatin-Resistant Bladder CancerSeiler, R. and Daugaard, M. et al. | May 1, 2017My team focuses on development of novel innovative technology for cancer therapeutics and diagnostics. A…sciencecityMay 1, 2017 Read More
Publications of the Week Impact of Molecular Subtypes in Muscle-Invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant ChemotherapySeiler, R. and Black, P.C., et al. | April 24, 2017An early report on the molecular subtyping of muscle-invasive bladder cancer (MIBC) by gene expression…sciencecityApril 24, 2017 Read More
Publications of the Week A Novel AHI-1-BCR-ABL-DNM2 Complex Regulates Leukemic Properties of Primitive Cml Cells through Enhanced Cellular Endocytosis and ROS-Mediated AutophagyLiu, X. and Jiang, X., et al. | April 17, 2017Tyrosine kinase inhibitor (TKI) therapies induce clinical remission with remarkable effects on chronic myeloid leukemia…sciencecityApril 17, 2017 Read More
Publications of the Week Depression, Telomeres and Mitochondrial DNA: Between- and Within-Person Associations from a 10-Year Longitudinal StudyPuterman, E., et al. | April 10, 2017Alterations in cellular aging, indexed by leukocyte telomere length (LTL) and mitochondrial DNA copy number…sciencecityApril 10, 2017 Read More
Publications of the Week Serotonin and Dopamine Transporter PET Changes in the Premotor Phase of LRRK2 Parkinsonism: Cross-Sectional StudiesWile, D.J. and Stoessl, A.J., et al. | April 3, 2017Background People with Parkinson's disease can show premotor neurochemical changes in the dopaminergic and non-dopaminergic…sciencecityApril 3, 2017 Read More
Publications of the Week Stromal Gene Expression Is Predictive for Metastatic Primary Prostate CancerMo, et al. | European Urology | March 27, 2017Background Clinical grading systems using clinical features alongside nomograms lack precision in guiding treatment decisions…sciencecityMarch 27, 2017 Read More
Publications of the Week Gentamicin B1 Is a Minor Gentamicin Component with Major Nonsense Mutation Suppression ActivityBaradaran-Heravi, et al. | March 20, 2017ABSTRACT: Nonsense mutations underlie about 10% of rare genetic disease cases. They introduce a premature termination…sciencecityMarch 20, 2017 Read More
Publications of the Week 18F-Fluorination of Unactivated C–H Bonds in Branched Aliphatic Amino Acids: Direct Synthesis of Oncological Positron Emission Tomography Imaging AgentsNodwell, M.B. et al. | March 13, 2017ABSTRACT: A mild and selective photocatalytic C-H 18F-fluorination reaction has been developed that provides direct…sciencecityMarch 13, 2017 Read More
Publications of the Week CLK-Dependent Exon Recognition and Conjoined Gene Formation Revealed with a Novel Small Molecule InhibitorNature Communications | March 8, 2017ABSTRACT: CDC-like kinase phosphorylation of serine/arginine-rich proteins is central to RNA splicing reactions. Yet, the…sciencecityMarch 8, 2017 Read More
Publications of the Week CX-5461 is a DNA G-Quadruplex Stabilizer with Selective Lethality in BRCA1/2 Deficient TumoursXu, H. et al. | February 27, 2017ABSTRACT: G-quadruplex DNAs form four-stranded helical structures and are proposed to play key roles in different…sciencecityFebruary 27, 2017 Read More