Publications of the Week Repeated Exposure to Sucrose for Procedural Pain in Mouse Pups Leads to Long-Term Widespread Brain AlterationsTremblay, S. and Grunau, R.E., et al. | August 4, 2017Oral sucrose is administered routinely to reduce pain of minor procedures in premature infants and…sciencecityAugust 4, 2017 Read More
Publications of the Week REVIEW: Targeting Fyn Kinase in Alzheimer’s DiseaseNygaard, H.B. | August 3, 2017The past decade has brought tremendous progress in unraveling the pathophysiology of Alzheimer's disease (AD).…sciencecityAugust 3, 2017 Read More
Publications of the Week HIT’nDRIVE: Patient-Specific Multi-Driver Gene Prioritization for Precision OncologyShrestha, R. and Sahinalp, C., et al. | August 2, 2017Prioritizing molecular alterations that act as drivers of cancer remains a crucial bottleneck in therapeutic…sciencecityAugust 2, 2017 Read More
Publications of the Week Gene Regulatory Networks for the Haploid-To-Diploid Transition of Chlamydomonas ReinhardtiiJoo, S. and Lee, J.H., et al. | July 31, 2017In brief, this publication describes the detailed gene-level execution of zygote development in the first…sciencecityJuly 31, 2017 Read More
Publications of the Week Assessing Structure and Function of Myelin in Cervical Spondylotic Myelopathy: Evidence of DemyelinationLiu, H. and Kramer, J.L.K., et al. | July 28, 2017For the first time, we have provided in vivo evidence of demyelination in individuals with…sciencecityJuly 28, 2017 Read More
Publications of the Week The Interactome of Metabolic Enzyme Carbonic Anhydrase IX Reveals Novel Roles in Tumor Cell Migration and Invadopodia/MMP14-Mediated InvasionSwayampakula, M. and Dedhar, S., et al | July 26, 2017Carbonic anhydrase IX (CAIX) is a hypoxia inducible factor 1-induced, cell surface pH regulating enzyme…sciencecityJuly 26, 2017 Read More
Publications of the Week REVIEW: Genes and Molecular Pathways Underpinning CiliopathiesLeroux, M.R., et al. | July 25, 2017Motile and non-motile (primary) cilia are nearly ubiquitous cellular organelles. The dysfunction of cilia causes…sciencecityJuly 25, 2017 Read More
Publications of the Week Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends LifespanTempleman, N.M. and Johnson, J.D., et al. | July 24, 2017Our well-powered study had two major findings, both of which have profound implications across multiple…sciencecityJuly 24, 2017 Read More
Publications of the Week Vitamin C-Induced Epigenomic Remodelling in IDH1 Mutant Acute Myeloid LeukaemiaMingay, M. and Hirst, M., et al. | July 21, 2017Mutations in genes encoding epigenetic regulators as well as mutations in the histones they modify…sciencecityJuly 21, 2017 Read More
Publications of the Week Loss-Of-Function and Gain-Of-Function Mutations in KCNQ5 Cause Intellectual Disability or Epileptic EncephalopathyLehman, A. and Claydon, T., et al. | July 19, 2017KCNQ5 is a highly conserved gene encoding an important channel for neuronal function; it is…sciencecityJuly 19, 2017 Read More