Publications of the Week Conserved and Unique Features of the Fission Yeast Core Atg1 ComplexNanji, T. and Yip, C.K., et al. | October 17, 2017Much of the published studies have focused on the Atg1 complex from budding yeast Saccharomyces…sciencecityOctober 17, 2017 Read More
Publications of the Week Successful Targeting of the NRG1 Pathway Indicates Novel Treatment Strategy for Metastatic CancerJones, M.R. and Laskin, J., et al. | October 12, 2017Oncogenic gene fusions involving Neuregulin 1 (NRG1) have been described as recurrent aberrations in lung…sciencecityOctober 12, 2017 Read More
Publications of the Week CD56bright NK Regulatory Cells in Filgrastim Primed Donor Blood or Marrow Products Regulate Chronic GvHD: CBMTG Randomized 0601 Study ResultsKariminia, A. and Schultz, K.R., et al. | October 10, 2017his is a major Canadian study performed by the Canadian BMT Group and including centres…sciencecityOctober 10, 2017 Read More
Publications of the Week REVIEW: Asthma-COPD Overlap Syndrome: Pathogenesis, Clinical Features, and Therapeutic TargetsLeung, J.M. and Sin, D.D. | October 9, 2017Asthma-COPD overlap syndrome (ACOS) or asthma-COPD overlap captures the subset of patients with airways disease…sciencecityOctober 9, 2017 Read More
Publications of the Week REVIEW: When Beta Cells Talk BackDenroche, H.C. and Verchere, C.B., et al. | October 5, 2017Islet macrophages reside in the perivascular space next to islet blood vessels. They are long-lived…sciencecityOctober 5, 2017 Read More
Publications of the Week Generation of a Multi-Antigen-Directed Immune Response for Durable Control of Acute Lymphoblastic LeukemiaJo, S. and Reid, G.S.D., et al. | October 3, 2017In this study we used a mouse model of acute lymphoblastic leukemia, the most common…sciencecityOctober 3, 2017 Read More
Publications of the Week Spinal Cord Perfusion Pressure Predicts Neurologic Recovery in Acute Spinal Cord InjurySquair, J.W. and Kwon, B.K., et al. | October 2, 2017In this study we inserted lumbar drains in patients with acute SCI, and evaluated how…sciencecityOctober 2, 2017 Read More
Publications of the Week Discovery of a Proteolytic Flagellin Family in Diverse Bacterial Phyla That Assembles Enzymatically Active FlagellaEckhard, U., et al. | September 29, 2017The bacterial flagellum is a complex multi-component structure including a whip-like appendage, the flagellar filament,…sciencecitySeptember 29, 2017 Read More
Publications of the Week Cortical Functional Hyperconnectivity in a Mouse Model of Depression and Selective Network Effects of KetamineMcGirr, A. and Murphy, T.H., et al. | September 28, 2017First, we show that models of depression in mouse produce brain function changes resembling those…sciencecitySeptember 28, 2017 Read More
Publications of the Week NEWS AND VIEWS: Interpreting the T-Cell Receptor RepertoireHolt, R.A. | September 26, 2017Engineered T-cell receptors (TCRs) have tremendous therapeutic potential for targeted, T-cell-mediated killing of infected or…sciencecitySeptember 26, 2017 Read More