Publications of the Week Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation Wang, Y., et al. | April 4, 2025 Prostate cancer remains one of the leading causes of cancer-related deaths among men, and understanding…karnottApril 4, 2025 Read More
Publications of the Week 5′-S-(3-Aminophenyl)-5′-Thioadenosine, a Novel Chemoprotective Agent for Reducing Toxic Side Effects of Fluorouracil in Treatment of MTAP-Deficient Cancers Zhang, S., et al. | March 27, 2025 Nucleobase analogue (NBA) drugs, such as 5-fluorouracil (5-FU), are effective chemotherapeutics, but their clinical use…karnottMarch 27, 2025 Read More
Publications of the Week Sanfetrinem, an Oral β-Lactam Antibiotic Repurposed for the Treatment of Tuberculosis Ramón-García, S., et al. | March 24, 2025 This week, we profile a recent publication in Drug Resistance Updates by Dr. Santiago Ramón-García…karnottMarch 24, 2025 Read More
Publications of the Week Type-2 Innate Signals Are Dispensable for Skeletal Muscle Regeneration and Pathology Linked to Duchenne Muscular Dystrophy Messing, M., et al. | March 18, 2025 Immune responses play an integral role in skeletal muscle regeneration. In the genetically inherited muscle…karnottMarch 18, 2025 Read More
Publications of the Week Epstein-Barr Virus Infection Promotes T Cell Dysregulation in a Humanized Mouse Model of Multiple Sclerosis Allanach, J., et al. | March 13, 2025 Latent infection with Epstein-Barr virus (EBV) is a strong risk factor for the development of…karnottMarch 13, 2025 Read More
Publications of the Week Brain Pericytes and Perivascular Fibroblasts Are Stromal Progenitors With Dual Functions in Cerebrovascular Regeneration After Stroke Bernier, L., et al. | March 10, 2025 Functional revascularization is key to stroke recovery and requires remodeling and regeneration of blood vessels…karnottMarch 10, 2025 Read More
Publications of the Week Single Cell Approaches Define Neural Stem Cell Niches and Identify Microglial Ligands That Can Enhance Precursor-Mediated Oligodendrogenesis Willis, A., et al. | March 6, 2025 Here, we used single cell RNA sequencing and single cell spatial transcriptomics to characterize the…karnottMarch 6, 2025 Read More
Publications of the Week Melatonin Supplementation and Oxidative DNA Damage Repair Capacity Among Night Shift Workers: A Randomised Placebo-Controlled Trial Zanif, U., et al. | March 4, 2025 A decreased ability to repair oxidative DNA damage, due to melatonin suppression, is a compelling…karnottMarch 4, 2025 Read More
Publications of the Week Alzheimer’s Disease Modeling and Drug Screening Through hiPSC 3D Bioprinting Sorrentino, S., et al. | February 27, 2025 Our current understanding of the molecular mechanisms underlying amyloidogenesis in Alzheimer’s Disease (AD) is limited…karnottFebruary 27, 2025 Read More
Publications of the Week Atypical Hippocampal Excitatory Neurons Express and Govern Object Memory Kinman, A., et al. | February 25, 2025 Classically, pyramidal cells of the hippocampus are viewed as flexibly representing spatial and non-spatial information.…karnottFebruary 25, 2025 Read More