Publications of the Week Deciphering the Biosynthesis of a Novel Lipid in Mycobacterium tuberculosis Expands the Known Roles of the Nitroreductase SuperfamilyGrigg, J. C., et al. | June 27, 2023Mycobacterium tuberculosis’s (Mtb) success as a pathogen is due in part to its sophisticated lipid…pthomsonJune 27, 2023 Read More
Publications of the Week Relapse Timing Is Associated With Distinct Evolutionary Dynamics in Diffuse Large B-Cell LymphomaHilston, L.K., et al. | June 21, 2023 Diffuse large B-cell lymphoma (DLBCL) is cured in more than 60% of patients, but outcomes…sciencecityJune 21, 2023 Read More
Publications of the Week GluN2B-Containing NMDARs in the Mammalian Brain: Pharmacology, Physiology, and PathologyGe, Y. and Wang, Y.T. | June 19, 2023Glutamate N-methyl-D-aspartate receptor (NMDAR) is critical for promoting physiological synaptic plasticity and neuronal viability. As…sciencecityJune 19, 2023 Read More
Publications of the Week Contrasting Outcomes of Genome Reduction in Mikrocytids and MicrosporidiansŽárský, V., & Karnkowska, A., et al. | June 13, 2023Intracellular symbionts often undergo genome reduction, losing both coding and non-coding DNA in a process…pthomsonJune 13, 2023 Read More
Publications of the Week A Bi-Functional PARP-HDAC Inhibitor with Activity in Ewing SarcomaRamos, L, et al. al. | June 12, 2023Purpose: Histone deacetylase (HDAC) inhibition has been shown to induce pharmacological “BRCAness” in cancer cells…pthomsonJune 12, 2023 Read More
Publications of the Week Cryo-EM Analysis of Scorpion Toxin Binding to Ryanodine Receptors Reveals Subconductance That Is Abolished by PKA PhosphorylationHaji-Ghassemi, O., et al. | June 8, 2023Calcins are peptides from scorpion venom with the unique ability to cross cell membranes, gaining…pthomsonJune 8, 2023 Read More
Publications of the Week Protocol Development to Further Differentiate and Transition Stem Cell-Derived Pancreatic Progenitors from a Monolayer into Endocrine Cells in Suspension CultureBraam, M. J. S., et al. | June 5, 2023The generation of functional β-cells from human pluripotent stem cells (hPSCs) for cell replacement therapy…pthomsonJune 5, 2023 Read More
Publications of the Week A Novel Cell-Based Screen Identifies Chemical Entities That Reverse the Immune-Escape Phenotype of Metastatic TumoursNohara, L., et al. | June 2, 2023Genetic and epigenetic events have been implicated in the downregulation of the cellular antigen processing…pthomsonJune 2, 2023 Read More
Publications of the Week Reference-Free Assembly of Long-Read Transcriptome Sequencing Data with RNA-Bloom2Nip, K. M., et al. | May 31, 2023Long-read sequencing technologies have improved significantly since their emergence. Their read lengths, potentially spanning entire…pthomsonMay 31, 2023 Read More
Publications of the Week A Combination of Genetically Engineered Oncolytic Virus and Melittin-CpG for Cancer Viro-Chemo-ImmunotherapyBahreyni, A., et al. | May 26, 2023Immunotherapy has emerged as an efficient therapeutic approach for cancer management. However, stimulation of host…pthomsonMay 26, 2023 Read More