Publications of the Week Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson’s DiseaseWiesman, A., et al. | July 4, 2025Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to…karnottJuly 4, 2025 Read More
Publications of the Week Human De Novo Mutation Rates From a Four-Generation Pedigree ReferencePorubsky, D., et al. | June 23, 2025Understanding the human de novo mutation (DNM) rate requires complete sequence information1. Here using five…karnottJune 23, 2025 Read More
Publications of the Week NOTCH1 Dimeric Signaling Is Essential for T-Cell Leukemogenesis and Leukemia MaintenanceTamiro, F., et al. | June 20, 2025T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy that is characterized by an expansion…karnottJune 20, 2025 Read More
Publications of the Week Functional Targeting of ILC2s and ILC3s Reveals Selective Roles in Intestinal Fibrosis and HomeostasisKabil, A., et al. | June 12, 2025Innate lymphoid cells (ILCs) are long-lived, tissue-resident cell analogs to T helper subsets that lack…karnottJune 12, 2025 Read More
Publications of the Week Recovery of Antibody Immunity After a Resurgence of Respiratory Syncytial Virus InfectionsReicherz, F., et al. | June 5, 2025Longitudinal measurements of respiratory syncytial virus (RSV) immunity over 4 winter seasons reveal that viral…karnottJune 5, 2025 Read More
Publications of the Week A Multi-Kingdom Genetic Barcoding System for Precise Clone IsolationIshiguro, S., et al. | May 28, 2025Cell-tagging strategies with DNA barcodes have enabled the analysis of clone size dynamics and clone-restricted…sciencecityMay 28, 2025 Read More
Publications of the Week Bat Organoids Reveal Antiviral Responses at Epithelial SurfacesKellner, M.J., et al. | May 27, 2025Bats can host viruses of pandemic concern without developing disease. The mechanisms underlying their exceptional…sciencecityMay 27, 2025 Read More
Publications of the Week Investigation of Integrase Inhibitor Resistance Mutations in gp41 in Clinical SamplesSudderuddin, H., et al. | May 23, 2025Mutations conferring resistance to HIV Integrase Strand Transfer Inhibitors (INSTI) can occur outside integrase, including…sciencecityMay 23, 2025 Read More
Publications of the Week Characterization of a Two-Component Kinase That Initiates the Bacterial Catabolism of HydroxyphenylethanonesDexter, G.N., et al. | May 22, 2025The prodigious ability of bacteria to catabolize aromatic compounds has sparked considerable efforts to engineer…sciencecityMay 22, 2025 Read More
Publications of the Week PI3K/AKT Signaling Mediates Stress-Inducible Amyloid Formation Through C-MycLacroix, E., et al. | May 12, 2025In response to environmental stress, eukaryotic cells reversibly form functional amyloid aggregates called amyloid bodies…karnottMay 12, 2025 Read More