Publications of the Week DNA Methylation Epitypes of Burkitt Lymphoma with Distinct Molecular and Clinical FeaturesThomas, N., et al. | August 1, 2025The genetic subtypes of Burkitt lymphoma have been defined, but the role of epigenetics remains…karnottAugust 1, 2025 Read More
Publications of the Week CXCR4-LASP1-G9a-Snail Axis Drives NEPC Transdifferentiation via Induction of EMT and Downregulation of RESTLiu, L., et al. | July 21, 2025Phenotypic switching is an emerging driver of cancer treatment resistance, yet early signals regulating this…karnottJuly 21, 2025 Read More
Publications of the Week Drug Tolerance and Persistence to EGFR Inhibitor Treatment Are Mediated by an ILK-SFK-YAP Signaling Axis in Lung AdenocarcinomaShi, R., et al. | July 16, 2025Combating resistance to targeted therapy remains a major challenge to improving lung cancer care. Epithelial-mesenchymal…karnottJuly 16, 2025 Read More
Publications of the Week Widespread and Cell-Type-Specific Transcriptomic Reorganization Following Mild Traumatic Brain InjurySwaro, A., et al. | July 8, 2025Knowledge of how traumatic brain injury (TBI) alters the brain is urgently needed. A major…karnottJuly 8, 2025 Read More
Publications of the Week Sensitivity of Diffusion Tensor Imaging to Regional Mixed Cerebrovascular PathologyFerris, J., et al. | July 7, 2025Diffusion tensor imaging is a candidate biomarker in cerebrovascular disease. Yet, little is known about…karnottJuly 7, 2025 Read More
Publications of the Week Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson’s DiseaseWiesman, A., et al. | July 4, 2025Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to…karnottJuly 4, 2025 Read More
Publications of the Week Human De Novo Mutation Rates From a Four-Generation Pedigree ReferencePorubsky, D., et al. | June 23, 2025Understanding the human de novo mutation (DNM) rate requires complete sequence information1. Here using five…karnottJune 23, 2025 Read More
Publications of the Week NOTCH1 Dimeric Signaling Is Essential for T-Cell Leukemogenesis and Leukemia MaintenanceTamiro, F., et al. | June 20, 2025T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy that is characterized by an expansion…karnottJune 20, 2025 Read More
Publications of the Week Functional Targeting of ILC2s and ILC3s Reveals Selective Roles in Intestinal Fibrosis and HomeostasisKabil, A., et al. | June 12, 2025Innate lymphoid cells (ILCs) are long-lived, tissue-resident cell analogs to T helper subsets that lack…karnottJune 12, 2025 Read More
Publications of the Week Recovery of Antibody Immunity After a Resurgence of Respiratory Syncytial Virus InfectionsReicherz, F., et al. | June 5, 2025Longitudinal measurements of respiratory syncytial virus (RSV) immunity over 4 winter seasons reveal that viral…karnottJune 5, 2025 Read More