Publications of the Week Photosystems in the Eye-like Organelles of Heterotrophic Warnowiid DinoflagellatesCooney, E.C., et al. | September 14, 2023Warnowiid dinoflagellates contain a highly complex camera-eye-like structure called the ocelloid that is composed of…sciencecitySeptember 14, 2023 Read More
Publications of the Week Nuclear Hormone Receptor NHR-49 Is an Essential Regulator of Stress Resilience and Healthy Aging in Caenorhabditis elegansDoering, K. R. S., et al. | September 4, 2023The genome of Caenorhabditis elegans encodes 284 nuclear hormone receptor, which perform diverse functions in…pthomsonSeptember 4, 2023 Read More
Publications of the Week Oligodendrocyte Pathology in Huntington’s Disease: From Mechanisms to TherapeuticsBardile, C. F., et al. | August 30, 2023Myelin, the lipid-rich structure formed by oligodendrocytes (OLGs) in the central nervous system, is fundamental…pthomsonAugust 30, 2023 Read More
Publications of the Week Comprehensive Cell Surface Protein Profiling of Human Mesenchymal Stromal Cells From Peritoneal Dialysis Effluent and Comparison With Those From Human Bone Marrow and Adipose TissueShi, G., et al. | August 29, 2023Peritoneal mesenchymal stromal cells (pMSCs) are isolated from peritoneal dialysis (PD) effluent, and treatment with…pthomsonAugust 29, 2023 Read More
Publications of the Week A MYCN-Independent Mechanism Mediating Secretome Reprogramming and Metastasis in MYCN-Amplified NeuroblastomaZhang, H., et al. | August 24, 2023MYCN amplification (MNA) is a defining feature of high-risk neuroblastoma (NB) and predicts poor prognosis. However,…pthomsonAugust 24, 2023 Read More
Publications of the Week A High-Throughput Screening Platform for Enzymes Active on Mucin-Type O-GlycoproteinsWardman, J. F., et al. | August 22, 2023Mucin-type O-glycosylation is a post-translational modification present at the interface between cells where it has…pthomsonAugust 22, 2023 Read More
Publications of the Week Cleavage of 14-3-3ε by the Enteroviral 3C Protease Dampens RIG-I-Mediated Antiviral SignalingAndrews, D. D. T., et al. | August 15, 2023Viruses have evolved diverse strategies to evade the host innate immune response and promote infection.…pthomsonAugust 15, 2023 Read More
Publications of the Week A Novel Class of Broad-Spectrum Active-Site-Directed 3C-Like Protease Inhibitors with Nanomolar Antiviral Activity against highly Immune-Evasive SARS-CoV-2 Omicron SubvariantsPérez-Vargas, J., et al. | August 14, 2023Antivirals with broad coronavirus activity are important for treating high-risk individuals exposed to the constantly…pthomsonAugust 14, 2023 Read More
Publications of the Week ASCL1 Is Activated Downstream of the ROR2/CREB Signaling Pathway to Support Lineage Plasticity in Prostate CancerTabrizian, N., et al. | August 11, 2023Lineage plasticity is a form of therapy-induced drug resistance. In prostate cancer, androgen receptor (AR)…pthomsonAugust 11, 2023 Read More
Publications of the Week DNA-PK Inhibition Extends the Therapeutic Effects of Top2 Poisoning to Non-Proliferating Cells, Increasing Activity at a CostWant, T., et al. | August 10, 2023Type II topoisomerase (Top2) poisoning therapy is used to treat a broad range of cancers…pthomsonAugust 10, 2023 Read More