The Onpattro Story and the Clinical Translation of Nanomedicines Containing Nucleic Acid-Based Drugs
The regulatory approval of Onpattro, a lipid nanoparticle-based short interfering RNA drug for the treatment…
sciencecityDecember 17, 2019
High YAP activity is associated with poor prognosis human breast cancers, but its role during…
sciencecityDecember 13, 2019
The authors have found that ELF3, a transcription factor, is a new amplified oncogene in…
sciencecityDecember 11, 2019
The authors used an automated tracking system to quantify 26 measures spanning morphology, locomotion, tactile…
sciencecityDecember 6, 2019
It has been shown that metastatic prostate cancers with mismatch repair defects are likely to…
sciencecityDecember 5, 2019
Loss-of-function variants in ZDHHC9 have been identified in patients with X-linked intellectual disability (XLID), with…
sciencecityDecember 3, 2019
The researchers conducted extensive analyses of the genomes, epigenomes and transcriptomes of Rhabdoid tumours (RTs)…
sciencecityNovember 29, 2019
Documenting the natural diversity of eukaryotic organisms in the nonhuman primate (NHP) gut is important…
sciencecityNovember 28, 2019
In Huntington disease (HD), the mutated HTT gene expresses with pathogenic gain-of-function activities. The authors…
sciencecityNovember 25, 2019
