Publications of the Week Complete Mitochondrial Genome of a Gymnosperm, Sitka Spruce (Picea Sitchensis), Indicates a Complex Physical Structure Jackman, S.D., et al. | June 15, 2020 The authors made use of both long- and short-read sequencing technologies to determine the complete…eabramovichJune 15, 2020 Read More
Publications of the Week Epigenetic And Functional Changes Imposed By NUP98-HOXA9 In A Genetically Engineered Model Of Chronic Myeloid Leukemia Progression Sloma, I., et al. | June 12, 2020 NUP98-HOXA9 (NA9) is a fusion gene commonly found in human acute myeloid leukemia (AML) cells…eabramovichJune 12, 2020 Read More
Publications of the Week T Reg-Specific Insulin Receptor Deletion Prevents Diet-Induced and Age-Associated Metabolic Syndrome Wu, D., et al. | June 11, 2020 The Levings’ lab works on understanding the biology of regulatory T cells so that they…eabramovichJune 11, 2020 Read More
Publications of the Week Epithelial-Interleukin-1 Inhibits Collagen Formation by Airway Fibroblasts: Implications for Asthma Osei, E.T., et al. | June 8, 2020 The authors found that there was increased release of IL-1α and its family member IL-1β…eabramovichJune 8, 2020 Read More
Publications of the Week Genetic Variants Drive Altered Epigenetic Regulation of Endotoxin Response in BTBR Macrophages Ciernia, A.V., et al. | June 4, 2020 This work examines how genetics and environment influence immune system regulation in a mouse model…eabramovichJune 4, 2020 Read More
Publications of the Week Activating AKT1 and PIK3CA Mutations in Metastatic Castration-Resistant Prostate Cancer Herberts, C., et al. | June 3, 2020 Activating mutations in AKT1 and PIK3CA are undercharacterised in metastatic castration-resistant prostate cancer (mCRPC), but…eabramovichJune 3, 2020 Read More
Publications of the Week Utilizing Organoid and Air-Liquid Interface Models as a Screening Method in the Development of New Host Defense Peptides Choi, K.Y.G., et al. | May 28, 2020 Host defense peptides (HDPs), also known as antimicrobial peptides, are naturally occurring polypeptides (~12–50 residues)…eabramovichMay 28, 2020 Read More
Publications of the Week Deregulated Regulators: Disease-Causing cis Variants in Transcription Factor Genes van der Lee, R., et al. | May 26, 2020 Challenges in the interpretation of whole-genome sequences leave rare disease cases undiagnosed. Cis-regulatory variants are anticipated…eabramovichMay 26, 2020 Read More
Publications of the Week Altered microRNA Expression Links IL6 and TNF-Induced Inflammaging with Myeloid Malignancy Grants, J.M., et al. | May 25, 2020 This study reveals how regulation of a microRNA links aging, inflammation and the development of…eabramovichMay 25, 2020 Read More
Publications of the Week Overexpression of the Small RNA PA0805.1 in Pseudomonas aeruginosa Modulates the Expression of a Large Set of Genes and Proteins, Resulting in Altered Motility, Cytotoxicity, and Tobramycin Resistance Coleman, S.R., et al. | May 21, 2020 Pseudomonas aeruginosa is a motile species that initiates swarming motility in response to specific environmental cues,…eabramovichMay 21, 2020 Read More