Publications of the Week Malt1 Blocks IL-1β Production by Macrophages in Vitro and Limits Dextran Sodium Sulfate-Induced Intestinal Inflammation in Vivo Monajemi, M. and Sly, L.M., et al. | June 25, 2018 Our laboratory is interested in providing molecular insights into the cause(s) and pathogenesis of intestinal…sciencecityJune 25, 2018 Read More
Publications of the Week Modulating Cell State to Enhance Suspension Expansion of Human Pluripotent Stem Cells Lipsitz, Y.Y. and Zandstra, P.W., et al. | June 20, 2018 The development of cell-based therapies to replace missing or damaged tissues within the body or…sciencecityJune 20, 2018 Read More
Publications of the Week Basal-like Breast Cancers: From Pathology to Biology and Back Again Gusterson, B. and Eaves, C.J. | June 18, 2018 Human breast cancers referred to as "basal-like" are of interest because they lack effective therapies…sciencecityJune 18, 2018 Read More
Publications of the Week Single-Cell Analysis Identifies a CD33+ Subset of Human Cord Blood Cells with High Regenerative Potential Knapp, D.J.H.F. and Eaves, C.J., et al. | June 15, 2018 In this publication we create functional and molecular maps of the blood stem cell compartment…sciencecityJune 15, 2018 Read More
Publications of the Week Phase 1 Trials of Anti-enpp3 Antibody Drug Conjugates in Advanced Refractory Renal Cell Carcinomas Thompson, J.A., and Kollmannsberger, C., et al. | June 13, 2018 To determine the safety, pharmacokinetics, and recommendedphase2 dose of an antibody drug conjugate (ADC) targeting…sciencecityJune 13, 2018 Read More
Publications of the Week A Molecular Network of the Aging Human Brain Provides Insights into the Pathology and Cognitive Decline of Alzheimer’s Disease Mostafavi, S. and Jager, P.L., et al. | June 11, 2018 There is a need for new therapeutic targets with which to prevent Alzheimer's disease (AD),…sciencecityJune 11, 2018 Read More
Publications of the Week Endoplasmic Reticulum-Plasma Membrane Contact Sites Integrate Sterol and Phospholipid Regulation Quon, E. and Beh, C.T., et al. | June 8, 2018 Although many of the "tether" proteins that staple the ER and the PM together had…sciencecityJune 8, 2018 Read More
Publications of the Week The Genome-Wide Rate and Spectrum of Spontaneous Mutations Differ Between Haploid and Diploid Yeast Sharp, N.P. and Otto, S.P., et al. | June 6, 2018 Species vary substantially in how genetic material is transmitted from one generation to the next.…sciencecityJune 6, 2018 Read More
Publications of the Week MAP Kinase Signalling: Interplays Between Plant PAMP- and Effector-Triggered Immunity Thulasi Devendrakumar, K. and Zhang, Y., et al. | June 1, 2018 In plants, mitogen-activated protein kinase (MAPK) cascades are involved in regulating many biological processes including…sciencecityJune 1, 2018 Read More
Publications of the Week Interpretable Dimensionality Reduction of Single Cell Transcriptome Data with Deep Generative Models Ding, J, and Shah, S.P., et al. | May 30, 2018 Single-cell RNA-sequencing has great potential to discover cell types, identify cell states, trace development lineages,…sciencecityMay 30, 2018 Read More