Publications of the Week Computational Identification of Micro-Structural Variations and Their Proteogenomic Consequences in Cancer Lin, Y.Y. and Sahinalp, S.C., et al. | January 3, 2018 Rapid advancement in high throughput genome and transcriptome sequencing (HTS) and mass spectrometry (MS) technologies…sciencecityJanuary 3, 2018 Read More
Publications of the Week REVIEW: Proteolytic Cleavage-Mechanisms, Function, And “Omic” Approaches for a Near-Ubiquitous Post-Translational Modification Klein, T. and Overall, C.M., et al. | January 2, 2018 Proteases enzymatically hydrolyze peptide bonds in substrate proteins, resulting in a widespread, irreversible posttranslational modification…sciencecityJanuary 2, 2018 Read More
Publications of the Week Multiple Reaction Monitoring Mass Spectrometry to Identify Novel Plasma Protein Biomarkers of Treatment Response in Cystic Fibrosis Pulmonary Exacerbations Roberts, J.M. and Quon, B.S., et al. | December 15, 2017 This is the first study in CF to evaluate early change in blood protein biomarkers…sciencecityDecember 15, 2017 Read More
Publications of the Week A New Lineage of Eukaryotes Illuminates Early Mitochondrial Genome Reduction Janouskovec, J. and Keeling, P.J., et al. | December 14, 2017 Read the Publication This week we profile a recent publication in Current Biology from the…sciencecityDecember 14, 2017 Read More
Publications of the Week REVIEW: Functional Horizontal Gene Transfer from Bacteria to Eukaryotes McCutcheon, J.P. and Husnik, F. | December 11, 2017 Bacteria influence eukaryotic biology as parasitic, commensal or beneficial symbionts. Aside from these organismal interactions,…sciencecityDecember 11, 2017 Read More
Publications of the Week Effects of Teriparatide and Risedronate on New Fractures in Post-Menopausal Women with Severe Osteoporosis (VERO): A Multicentre, Double-Blind, Double-Dummy, Randomised Controlled Trial Kendler, D.L. and Lopez-Romero, P., et al. | December 8, 2017 The VERO study is the first properly designed and powered clinical trial comparing antiresorptive with…sciencecityDecember 8, 2017 Read More
Publications of the Week Diverse Marinimicrobia Bacteria May Mediate Coupled Biogeochemical Cycles along Eco-Thermodynamic Gradients Hawley, A.K. and Hallam, S.J., et al. | December 7, 2017 We are interested in developing enrichment or cultivation approaches needed to directly test the hypotheses…sciencecityDecember 7, 2017 Read More
Publications of the Week Localization and Functional Characterization of the P.Asn965Ser (N965S) ABCA4 Variant in Mice Reveal Pathogenic Mechanisms Underlying Stargardt Macular Degeneration Molday, L.L. and Molday, R.S., et al. | December 6, 2017 In this paper we have generated and characterized a mouse model for Stargardt disease in…sciencecityDecember 6, 2017 Read More
Publications of the Week REVIEW: Engineered Tolerance: Tailoring Development, Function, and Antigen-Specificity of Regulatory T Cells Dawson, N.A.J. and Levings, M.K., et al. | December 5, 2017 Regulatory T cells (Tregs) are potent suppressors of immune responses and are currently being clinically…sciencecityDecember 5, 2017 Read More
Publications of the Week Bacterially Derived Synthetic Mimetics of Mammalian Oligomannose Prime Antibody Responses That Neutralize HIV Infectivity Pantophlet, R. and Kosma, P., et al. | December 4, 2017 There are many scientific challenges to the design of a broadly effective HIV vaccine. One…sciencecityDecember 4, 2017 Read More